Dynamic changes of cerebrospinal fluid in upright and recumbent shunted experimental animals.

Child's Brain
S YamadaP L Perot

Abstract

The effect of positional change on intracranial CSF pressure, valve flow rates and atrial pressures were studied in 40 experimental dogs. The flow rate with a 30 to 60 mm H2O Holter valve changed from the recumbent to the head-up position: during the first minute it increased 2 1/2 times and then progressively decreased to become stabilized 20-30 min later at a value slightly lower than the head-up value. At the same time pressure dropped rapidly to -23 mm H2O and then slowly, during 30 min to -120 mm H2O. In dogs without a shunt the pressure drop was initially similar to that of shunted dogs but recovered to almost the initial positive pressure in 30 min. The flow rate from a reservoir to the atrium through a shunt system when changing to the head-up position showed a siphon effect. Atrial pressure does not change with positioning. The findings were similar with cisternal-peritoneal shunts. Flow rate, therefore, increase in the head-up position. Negative intracranial CSF pressure was due to a siphon effect through the shunt system.

Citations

Jan 1, 1985·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·I L el-Shafei
Jan 1, 1987·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·M MatsumaeO Sato
Feb 1, 1987·Journal of Neurosurgery·C Sainte-RoseJ F Hirsch
Mar 1, 1988·Journal of Neurosurgery·E L Foltz, J P Blanks
Jan 1, 1980·Acta neurochirurgica·A J DrapkinW C Yang
Nov 28, 2009·The Veterinary Clinics of North America. Small Animal Practice·William B Thomas

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