Dynamic Encoding of Effort and Reward throughout the Execution of Action by External Globus Pallidus Neurons in Monkeys

Journal of Cognitive Neuroscience
Simon Nougaret, Sabrina Ravel

Abstract

Humans and animals must evaluate the costs and expected benefits of their actions to make adaptive choices. Prior studies have demonstrated the involvement of the basal ganglia in this evaluation. However, little is known about the role of the external part of the globus pallidus (GPe), which is well positioned to integrate motor and reward-related information, in this process. To investigate this role, the activity of 126 neurons was recorded in the associative and limbic parts of the GPe of two monkeys performing a behavioral task in which different levels of force were required to obtain different amounts of liquid reward. The results first revealed that the activity of associative and limbic GPe neurons could be modulated not only by cognitive and limbic but also motor information at the same time, both during a single period or during different periods throughout the trial, mainly in an independent way. Moreover, as a population, GPe neurons encoded these types of information dynamically throughout the trial, when each piece of information was the most relevant for the achievement of the action. Taken together, these results suggest that GPe neurons could be dedicated to the parallel monitoring of task parameters essential...Continue Reading

References

Jan 1, 1991·Experimental Brain Research·P ApicellaW Schultz
Oct 1, 1989·Trends in Neurosciences·R L AlbinJ B Penney
Jan 1, 1987·Experimental Brain Research·S J MitchellM R DeLong
May 1, 1971·Journal of Neurophysiology·M R DeLong
Sep 1, 1972·Medical & Biological Engineering·E G Merrill, A Ainsworth
Aug 1, 1994·Brain : a Journal of Neurology·K P Bhatia, C D Marsden
Mar 1, 1993·The Journal of Comparative Neurology·S N HaberS J Mitchell
Mar 1, 1997·Journal of Neurophysiology·R S Turner, M E Anderson
Aug 15, 1998·Journal of Neurophysiology·J R HollermanW Schultz
Apr 9, 1999·Nature Neuroscience·J R Hollerman, W Schultz
Aug 3, 2000·Journal of Anatomy·J P BolamM D Bevan
Aug 15, 2001·The Journal of Comparative Neurology·H Kita, T Kita
Mar 4, 2003·Journal of Neurophysiology·Howard C Cromwell, Wolfram Schultz
Aug 5, 2004·Brain : a Journal of Neurology·David GrabliLéon Tremblay
Nov 13, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·David ArkadirHagai Bergman
Mar 29, 2005·Nature Neuroscience·Christelle BaunezMarianne Amalric
Jul 14, 2005·Neuroreport·Yassine DarbakyPaul Apicella
Aug 5, 2005·European Archives of Psychiatry and Clinical Neuroscience·Hendrik BielauBruno Baumann
Nov 29, 2005·Science·Kazuyuki SamejimaMinoru Kimura
Feb 3, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Benjamin PasquereauThomas Boraud
Mar 9, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Shlomo EliasHagai Bergman
May 23, 2007·Journal of Neuroscience Methods·Eric Maris, Robert Oostenveld
Mar 18, 2008·Brain : a Journal of Neurology·Liane SchmidtMathias Pessiglione
May 10, 2008·Neuron·Brian Lau, Paul W Glimcher
Dec 5, 2008·Journal of Neurophysiology·Mati JoshuaHagai Bergman
Oct 9, 2012·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Yulia WorbeLéon Tremblay
Dec 18, 2012·Neuromodulation : Journal of the International Neuromodulation Society·Fabián PiedimonteOsvaldo Vilela Filho
Feb 5, 2013·Nature Neuroscience·Christopher J PeckC Daniel Salzman
Oct 11, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Yosuke SagaEiji Hoshi
May 7, 2015·The European Journal of Neuroscience·Juan-Francisco Espinosa-ParrillaPaul Apicella
Aug 12, 2015·The European Journal of Neuroscience·Maria Imelda NoblejasHagai Bergman
Nov 13, 2015·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Simon Nougaret, Sabrina Ravel
Jan 19, 2016·Neuron·Nicolas MalletJoshua D Berke

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Citations

May 12, 2019·Movement Disorders : Official Journal of the Movement Disorder Society·Alberto CacciolaAngelo Quartarone
Nov 3, 2021·Scientific Reports·Simon NougaretAldo Genovesio

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