Dynamic nano-interfaces enable harvesting of functional 3D-engineered tissues

Advanced Healthcare Materials
Akihiro NishiguchiMitsuru Akashi

Abstract

Functional 3D-engineered tissues are successfully harvested from a substrate using stimuli-responsive hydrogel films with dynamic nano-interface. The dynamic wettability control at the interfaces allows cellular detachment, leading to tissue harvesting without serious damage and remaining polymers. This method can be applied to various types of organs and used for tissue transplantation in regenerative medicine.

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Citations

Jan 26, 2018·Advanced Healthcare Materials·Jonas C Rose, Laura De Laporte
Feb 1, 2017·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Paiyz E MikaelSyam P Nukavarapu
Aug 5, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Masamichi NakayamaTeruo Okano
Oct 9, 2020·Lasers in Surgery and Medicine·Vesna KaricHeidi Abrahamse
Aug 12, 2019·ACS Biomaterials Science & Engineering·Miyeon NohNathaniel S Hwang
Nov 18, 2021·Advanced Science·Claire BomkampElizabeth A Specht

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