Dynamic NMR spectroscopy of three 2,2'-dialkyl/aryl-1-picrylhydrazines in liquid solution

Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
K C BrownJ A Weil

Abstract

We have studied and compared the proton nuclear magnetic resonance spectra of a series of three 2,2'-di(alkyl/aryl)-1-(2,4,6-trinitrophenyl)hydrazines at 500 MHz in liquid toluene-d(8), with a view to learning details of the internal conformation changes taking place, as a function of temperature. Herein "alkyl" denotes 'methyl', and "aryl" denotes 'phenyl'. The synthesis and characterization of 2-phenyl,2'-methyl-1-picrylhydrazine is reported. One goal of the present study was to afford a comparison with the oxidation products, i.e., the three corresponding hydrazyl free radicals - which show striking differences. All the hydrazine molecules in liquid solution occur as interconverting enantiomorphic pairs (atropisomers). Advanced techniques for obtaining the relevant activation energies and pseudo-thermodynamic parameters (Arrhenius and Eyring) have been utilized, and these parameters are listed and discussed. The three hydrazines turn out be very similar with respect to their internal dynamics.

References

Jan 1, 1982·Clinical and Experimental Hypertension. Part B, Hypertension in Pregnancy·B Sandström
Apr 25, 2000·Acta Crystallographica. Section C, Crystal Structure Communications·J W QuailM P Singh
Apr 9, 2002·Journal of Biosciences·Athel Cornish-Bowden
Aug 14, 2003·Journal of the American Chemical Society·Ryan A OlsenLeonard J Mueller
Jul 13, 2006·The Journal of Physical Chemistry. a·Garett M LeskowitzLeonard J Mueller

❮ Previous
Next ❯

Citations

Aug 6, 2010·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·J A WeilJ Yu

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

International Journal of Peptide and Protein Research
M B Sankaram, K R Easwaran
Journal of Environmental Pathology, Toxicology and Oncology : Official Organ of the International Society for Environmental Toxicology and Cancer
Jeannine H Powell, Peter M Gannett
© 2022 Meta ULC. All rights reserved