Dynamic organization of lymphocyte plasma membrane: lessons from advanced imaging methods.

Immunology
Dylan M OwenMarek Cebecauer

Abstract

Lipids and lipid domains are suggested to play an essential role in the heterogeneous organization of the plasma membrane in eukaryotic cells, including cells of the immune system. We summarize the results of advanced imaging and physical studies of membrane organization with special focus on the plasma membrane of lymphocytes. We provide a comprehensive up-to-date view on the existence of membrane lipid and protein clusters such as lipid rafts and suggest research directions to better understand these highly dynamic entities on the surface of immune cells.

References

Oct 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·M B Sankaram, T E Thompson
Jan 1, 1985·Annual Review of Biophysics and Biophysical Chemistry·T E Thompson, T W Tillack
Aug 23, 1988·Biochemistry·K Simons, G van Meer
Aug 1, 1987·The Journal of Cell Biology·E Yechiel, M Edidin
Feb 18, 1972·Science·S J Singer, G L Nicolson
Jun 5, 1997·Nature·K Simons, E Ikonen
Mar 17, 1998·Biochemical and Biophysical Research Communications·M CebecauerV Horejsí
May 2, 1998·Biochimica Et Biophysica Acta·T X Xiang, B D Anderson
Jan 19, 1999·Annual Review of Cell and Developmental Biology·D A Brown, E London
Jun 8, 1999·Annual Review of Immunology·K C GarciaI A Wilson
Aug 4, 1999·Immunology Today·V HorejsíH Stockinger
Jun 1, 2000·The Journal of Cell Biology·B S WilsonJ M Oliver
Jun 12, 2002·The Journal of Cell Biology·Takahiro FujiwaraAkihiro Kusumi
Oct 18, 2002·European Journal of Immunology·Paola PizzoAntonella Viola
Dec 5, 2002·Current Opinion in Structural Biology·Nancy L ThompsonNoah W Allen
Jan 16, 2003·The Journal of Cell Biology·Ian A PriorJohn F Hancock
Nov 19, 2003·Cell·Sean Munro
Mar 23, 2004·Molecular Biology of the Cell·Bridget S WilsonJanet M Oliver
Dec 8, 2004·Seminars in Immunology·Hai-Tao HeDidier Marguet
Apr 5, 2005·The Journal of Biological Chemistry·Marek CebecauerImmanuel F Luescher
Aug 10, 2005·The Journal of Experimental Medicine·Wolfgang W A SchamelBalbino Alarcón
Oct 4, 2005·Biophysical Journal·Laure WawrezinieckPierre-François Lenne
Oct 6, 2005·The Journal of Cell Biology·Katharina GausThomas Harder
Oct 12, 2005·The Journal of Experimental Medicine·Gabriele CampiMichael L Dustin
Oct 15, 2005·Proceedings of the National Academy of Sciences of the United States of America·Sarah J PlowmanJohn F Hancock
Nov 8, 2005·Biophysical Journal·Stefanie Y NishimuraW E Moerner
Jul 22, 2006·The EMBO Journal·Pierre-François LenneDidier Marguet
Aug 10, 2006·Nature Methods·Michael J RustXiaowei Zhuang

❮ Previous
Next ❯

Citations

Jan 1, 2013·Computational and Structural Biotechnology Journal·Victoria C CoggerDavid G Le Couteur
Sep 3, 2011·Journal of Neurochemistry·Ningfeng TangCynthia F Bearer
Nov 17, 2011·Seminars in Cell & Developmental Biology·Pauline GonnordChristophe Lamaze
Sep 4, 2012·Biochimica Et Biophysica Acta·Carlos de la HabaAntoni Morros
Aug 21, 2013·Biochimica Et Biophysica Acta·Carlos de la HabaPaz Martínez
Oct 18, 2016·Frontiers in Cell and Developmental Biology·Jorge Bernardino de la SernaMarek Cebecauer
Jan 13, 2018·Frontiers in Cell and Developmental Biology·Marek Cebecauer, David Holowka
Apr 20, 2019·Frontiers in Immunology·Daniela Glatzová, Marek Cebecauer
Jul 28, 2020·Frontiers in Immunology·Sibel KaraAnja Lux

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.