Dynamically adaptive mesh refinement technique for image reconstruction in optical tomography

Applied Optics
Vadim Y Soloviev, Lada V Krasnosselskaia

Abstract

A novel adaptive mesh technique is introduced for problems of image reconstruction in luminescence optical tomography. A dynamical adaptation of the three-dimensional scheme based on the finite-volume formulation reduces computational time and balances the ill-posed nature of the inverse problem. The arbitrary shape of the bounding surface is handled by an additional refinement of computational cells on the boundary. Dynamical shrinking of the search volume is introduced to improve computational performance and accuracy while locating the luminescence target. Light propagation in the medium is modeled by the telegraph equation, and the image-reconstruction algorithm is derived from the Fredholm integral equation of the first kind. Stability and computational efficiency of the introduced method are demonstrated for image reconstruction of one and two spherical luminescent objects embedded within a breastlike tissue phantom. Experimental measurements are simulated by the solution of the forward problem on a grid of 5x5 light guides attached to the surface of the phantom.

References

Jul 1, 1997·Photochemistry and Photobiology·E M Sevick-MuracaC L Hutchinson
Jan 10, 2003·Applied Optics·Vadim SolovievSergei Vinogradov
May 30, 2003·Medical Physics·Xuejun GuHuabei Jiang
Jun 7, 2003·Applied Optics·Adam B MilsteinR P Millane
Apr 1, 1997·Applied Optics·J S ReynoldsD Ben-Amotz
Nov 1, 2004·Optics Express·Amit JoshiEva Sevick-Muraca
Jan 15, 1996·Optics Letters·M A O'LearyA G Yodh

❮ Previous
Next ❯

Citations

Jul 17, 2010·Medical Physics·Nicolas DucrosFrançoise Peyrin
Nov 14, 2015·Photonics·Andrew Edmans, Xavier Intes
May 2, 2008·Applied Optics·Vadim Y SolovievSimon R Arridge
Jan 25, 2011·Biomedical Optics Express·Vadim Y SolovievSimon R Arridge
Oct 24, 2007·Applied Optics·Vadim Y SolovievSimon R Arridge
Apr 21, 2007·Applied Optics·Vadim Y Soloviev
Dec 25, 2008·Applied Optics·Vadim Y SolovievSimon R Arridge
Dec 21, 2011·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Vadim Y SolovievSimon R Arridge

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.