Dynamics and diverse functions of nuclear pore complex proteins.

Nucleus
Guillaume Chatel, Birthe Fahrenkrog

Abstract

Nuclear pore complexes (NPCs) are best known for their central role in controlling the molecular trafficking between the cytoplasm and the nucleus. NPCs are assembled from about 30 different proteins and a growing body of evidence suggests that these nucleoporins are not only acting in the context of NPCs, but also in the nucleoplasm and cytoplasm. In this context it is well accepted that a set of nucleoporins are important regulators of a variety of mitotic processes, including kinetochore assembly, spindle checkpoint control and cytokinesis, whereas others associate with chromatin and administer gene expression. However, the functional importance of nucleoporins go far beyond these roles and this review will provide an overview of the latest insights into the versatility of metazoan nucleoporins with an emphasis on their roles in cell migration, cellular signaling and tissue-specific activities.

References

Jul 1, 1991·The Journal of Cell Biology·D R FinlayD J Forbes
Jul 13, 1995·Nature·N YokoyamaU Aebi
Feb 18, 1997·Proceedings of the National Academy of Sciences of the United States of America·P A FerreiraG H Travis
Nov 13, 1998·The Journal of Cell Biology·B FahrenkrogN Panté
Apr 15, 1999·The EMBO Journal·S NakielnyG Dreyfuss
May 12, 2000·Journal of Structural Biology·N PantéR Bastos
Jun 27, 2001·The Journal of Cell Biology·D J DilworthJ D Aitchison
Jan 17, 2002·Cell·Andrea PichlerFrauke Melchior
Jan 26, 2002·Science·Jost EnningaBeatriz M A Fontoura
Apr 16, 2002·Molecular Biology of the Cell·Eric R GriffisMaureen A Powers
May 29, 2002·The EMBO Journal·Olivier KirshAnne Dejean
Jul 10, 2002·The Journal of Cell Biology·Tobias C WaltherMaarten Fornerod
Dec 20, 2002·Journal of Structural Biology·Birthe FahrenkrogUeli Aebi
Aug 15, 2003·The Journal of Biological Chemistry·Lan XuJoan Massagué
Sep 10, 2003·The Journal of Cell Biology·Davide SalinaBrian Burke
Oct 23, 2003·Nature Reviews. Molecular Cell Biology·Birthe Fahrenkrog, Ueli Aebi
Jan 14, 2004·Molecular Biology of the Cell·Eric R GriffisMaureen A Powers
Oct 27, 2004·Nature Cell Biology·Gwénaël RabutJan Ellenberg
Apr 20, 2005·Current Opinion in Structural Biology·Thomas U Schwartz
May 24, 2005·Nature Cell Biology·Alexei ArnaoutovMary Dasso
Jul 28, 2005·Journal of Molecular Biology·Sara M PaulilloBirthe Fahrenkrog
Sep 1, 2005·Chromosoma·Jennifer R Ball, Katharine S Ullman
Feb 8, 2006·Proceedings of the National Academy of Sciences of the United States of America·Damien DevosAndrej Sali
Apr 25, 2006·Current Opinion in Cell Biology·Roderick Y H Lim, Birthe Fahrenkrog
Sep 12, 2006·Journal of Molecular Biology·Sara M PaulilloBirthe Fahrenkrog
Apr 6, 2007·Cell Motility and the Cytoskeleton·Maria Giovanna RiparbelliGiuliano Callaini
Jun 5, 2007·Journal of Molecular Biology·Kyrill Schwarz-HerionBirthe Fahrenkrog

❮ Previous
Next ❯

Citations

Oct 24, 2012·Nature Reviews. Molecular Cell Biology·Marcela Raices, Maximiliano A D'Angelo
Mar 25, 2014·Seminars in Cancer Biology·Akiko Takeda, Nabeel R Yaseen
Nov 14, 2014·Genes·Steven J SchnellWeidong Yang
Oct 17, 2015·Cellular and Molecular Life Sciences : CMLS·Daisuke Takao, Kristen J Verhey
May 2, 2014·Nucleus·Ilknur SurAngelika A Noegel
Dec 22, 2016·Nature Reviews. Molecular Cell Biology·Martin Beck, Ed Hurt
Feb 22, 2017·ELife·Juliana S CapitanioRichard W Wozniak
Nov 6, 2015·Cells·Ikram Mossaid, Birthe Fahrenkrog
Nov 28, 2013·G3 : Genes - Genomes - Genetics·Anita G FernandezFabio Piano
Aug 8, 2019·Cell Division· HartonoRichard W Wong
Aug 21, 2019·Journal of Cell Science·Bouchra KhalafPaolo Macchi
Jan 24, 2019·Cells·Adélia Mendes, Birthe Fahrenkrog
Oct 27, 2020·Frontiers in Neurology·Lisa Diez, Susanne Wegmann
Apr 17, 2013·Journal of Cell Science·Scott Nelson, Inke S Näthke

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cell Migration

Cell migration is involved in a variety of physiological and pathological processes such as embryonic development, cancer metastasis, blood vessel formation and remoulding, tissue regeneration, immune surveillance and inflammation. Here is the latest research.