Dynamics of change in self-reported disability among persons with Parkinson's disease after 2 years of follow-up

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Tatjana GazibaraTatjana Pekmezovic

Abstract

Symptoms of Parkinson's disease (PD) progress over time causing significant disability. Yet, change in disability over shorter time periods has not been entirely understood. The purpose of this study was to assess the Self-Assessment Disability Scale (SADS) in persons with Parkinson's disease (PD) after 2 years of follow-up and compare it with the score observed at baseline. Additionally, we aimed at evaluating association of motor and non-motor PD features at baseline with a higher disability after 2 years of follow-up. A total of 120 consecutive persons with PD, who denied falling in the past 6 months, were initially recruited. After 2 years of follow-up, 88 (73.3%) persons with PD were evaluated for SADS. The total disability (SADS) score did not change after follow-up (p = 0.529). We observed increase in difficulty at "Getting out of bed" (p = 0.006), "Getting up out of armchair" (p = 0.013), "Walking about house/flat" (p = 0.003), "Walking outside" (p = 0.010), and "Traveling by public transport" (p = 0.014). After adjusting for several potential confounding factors, falls in the past year (β = 8.32, 95% confidence interval (CI) 1.04-15.59) and higher Unified Parkinson's Disease Rating Scale part 3 at baseline (β = 0.26, 9...Continue Reading

References

Mar 1, 1992·Journal of Neurology, Neurosurgery, and Psychiatry·A J HughesA J Lees
Sep 1, 1989·Archives of Neurology·R G BrownC D Marsden
May 1, 1967·Neurology·M M Hoehn, M D Yahr
Dec 1, 1967·The British Journal of Social and Clinical Psychology·M Hamilton
May 2, 2001·Clinical Rehabilitation·M A BiemansL H van der Woude
Jan 1, 1959·The British Journal of Medical Psychology·M HAMILTON
Nov 20, 2004·Movement Disorders : Official Journal of the Movement Disorder Society·Mariese A HelyRobert Trafficante
Nov 2, 2006·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Pablo Martinez-MartinMaria João Forjaz
Nov 26, 2008·Movement Disorders : Official Journal of the Movement Disorder Society·Christopher G GoetzUNKNOWN Movement Disorder Society UPDRS Revision Task Force
Feb 10, 2009·Movement Disorders : Official Journal of the Movement Disorder Society·Anette SchragRichard Dodel
Nov 17, 2009·Lancet Neurology·Maria C Rodriguez-OrozJosé A Obeso
Nov 12, 2010·Movement Disorders : Official Journal of the Movement Disorder Society·Claire L TomlinsonCarl E Clarke
Jul 24, 2012·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Y H HiorthJ P Larsen
Feb 28, 2013·Geriatrics & Gerontology International·Tatjana GazibaraTatjana Pekmezovic
Mar 16, 2013·Reviews in the Neurosciences·Rita Grazina, João Massano
Mar 29, 2013·Movement Disorders : Official Journal of the Movement Disorder Society·Daniel M CorcosCynthia L Comella
Jan 25, 2014·BMC Neurology·Beata LindholmMaria H Nilsson
Apr 30, 2014·Geriatrics & Gerontology International·Tatjana GazibaraMarina Svetel
Sep 3, 2014·Parkinsonism & Related Disorders·Melissa J ArmstrongLisa M Shulman
Oct 5, 2014·Journal of Neurology, Neurosurgery, and Psychiatry·Roberto CiliaGianni Pezzoli
Dec 30, 2014·Movement Disorders : Official Journal of the Movement Disorder Society·Brook GalnaLynn Rochester
Jan 2, 2015·Neurology·Colleen G CanningVictor S C Fung
Mar 19, 2015·European Journal of Epidemiology·Tatjana GazibaraVladimir S Kostic
Dec 15, 2015·Journal of Neurologic Physical Therapy : JNPT·David SparrowTerry Ellis
Feb 16, 2016·Parkinsonism & Related Disorders·Terry D EllisLeland E Dibble
Feb 28, 2016·Archives of Gerontology and Geriatrics·Tatjana GazibaraTatjana Pekmezovic
Jul 2, 2016·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Dronacharya LamichhaneLisa M Shulman

❮ Previous
Next ❯

Citations

Nov 7, 2019·Acta Neurologica Scandinavica·Maria SperensGun-Marie Hariz
Sep 7, 2018·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Shan KangHong Jiang
May 13, 2018·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Tamer YazarSoner Çankaya
Mar 29, 2021·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Amir DanaAlireza Bahrami

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Tatjana GazibaraTatjana Pekmezovic
© 2022 Meta ULC. All rights reserved