Dynamics of Phospholipid Membranes beyond Thermal Undulations

The Journal of Physical Chemistry Letters
Sudipta GuptaGerald J Schneider

Abstract

We investigated the molecular dynamics of unilamellar liposomes by neutron spin echo spectroscopy. We report the first experimental evidence of a short-range motion at the length scale of the size of the headgroup of a lipid. The associated mean squared displacement shows a t0.26 dependence in the pico- to nanosecond region that indicates another process beyond the predictions of the Zilman-Granek (ZG) model ( t0.66) and translational diffusion ( t1). A comparison with theory shows that the observed low exponent is associated with a non-Gaussian transient trapping of lipid molecules in a local area and supports the continuous time random walk model. The analysis of the mean squared displacement leads to the important conclusion that the friction at the interface between water and liposomes plays a minor role. Center of mass diffusion of liposomes and transient trapping of lipids define the range in which the ZG model can be applied to analyze membrane fluctuations.

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Citations

Mar 13, 2020·Soft Matter·Sudipta Gupta, Gerald J Schneider
Sep 6, 2019·Physical Chemistry Chemical Physics : PCCP·V K SharmaE Mamontov
Jun 21, 2020·Scientific Reports·Sudipta GuptaGerald J Schneider
Jul 22, 2020·Physical Review. E·Pengbo XuWeihua Deng
Nov 18, 2018·Interface Focus·E E WeatherillM I Wallace
Feb 20, 2020·Physical Review. E·Cheng-Zhi XieYi-Fan Chen
Feb 12, 2021·Langmuir : the ACS Journal of Surfaces and Colloids·Judith U De MelGerald J Schneider
Oct 24, 2020·Structural Dynamics·Elizabeth G KelleyBela Farago
Apr 29, 2021·Soft Matter·Rasangi M PereraGerald J Schneider
Jun 26, 2021·The Journal of Physical Chemistry. B·Pallavi KumariAntonio Benedetto
Jul 9, 2021·Soft Matter·Sudipta Gupta, Rana Ashkar
Jul 31, 2021·Langmuir : the ACS Journal of Surfaces and Colloids·Judith U De MelGerald J Schneider
Dec 21, 2018·The Journal of Physical Chemistry. B·Caterina RicciRita Carrotta
Jul 17, 2020·Langmuir : the ACS Journal of Surfaces and Colloids·Judith U De MelGerald J Schneider
Oct 8, 2019·The Journal of Physical Chemistry. a·Kaicheng Zhu, Haibin Su
Jul 11, 2019·The Journal of Physical Chemistry. B·Wai Cheng WongChia-Lung Hsieh
May 24, 2019·The Journal of Physical Chemistry. B·Rony Granek
May 24, 2019·The Journal of Physical Chemistry. B·Sudipta GuptaGerald J Schneider
Mar 13, 2020·The Journal of Physical Chemistry. a·Kaicheng Zhu, Haibin Su

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