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Dynamics of PTH-induced disassembly of Npt2a/NHERF-1 complexes in living OK cells

American Journal of Physiology. Renal Physiology

Nov 5, 2010

Edward J WeinmanThomas A Blanpied

Abstract

Parathyroid hormone (PTH) inhibits the reabsorption of phosphate in the renal proximal tubule by disrupting the binding of the sodium-dependent phosphate transporter 2A (Npt2a) to the adapter protein sodium-hydrogen exchanger regulatory factor-1 (NHERF-1), a process initiated by activat...read more

Mentioned in this Paper

Parathyroid Hormone Peptide (1-34)
Establishment and Maintenance of Localization
PTH protein, human
Biosensors
Complex (molecular entity)
Sodium-Hydrogen Antiporter
Protoplasm
Inorganic Phosphate Transporter
Recombinant parathyroid hormone
Apical Membrane
Paper Details
References
  • References19
  • Citations13
12
  • References19
  • Citations13
12

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Related Papers

American Journal of Physiology. Renal Physiology

PTH transiently increases the percent mobile fraction of Npt2a in OK cells as determined by FRAP

American Journal of Physiology. Renal PhysiologyOctober 2, 2009
E J WeinmanMark Donowitz
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Dynamics of PTH-induced disassembly of Npt2a/NHERF-1 complexes in living OK cells

American Journal of Physiology. Renal Physiology

Nov 5, 2010

Edward J WeinmanThomas A Blanpied

PMID: 21048030

DOI: 10.1152/ajprenal.00532.2010

Abstract

Parathyroid hormone (PTH) inhibits the reabsorption of phosphate in the renal proximal tubule by disrupting the binding of the sodium-dependent phosphate transporter 2A (Npt2a) to the adapter protein sodium-hydrogen exchanger regulatory factor-1 (NHERF-1), a process initiated by activat...read more

Mentioned in this Paper

Parathyroid Hormone Peptide (1-34)
Establishment and Maintenance of Localization
PTH protein, human
Biosensors
Complex (molecular entity)
Sodium-Hydrogen Antiporter
Protoplasm
Inorganic Phosphate Transporter
Recombinant parathyroid hormone
Apical Membrane

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Human Vascular Endothelial Cell Atlas: Young & Old

Examining the genomics, transcriptomics, proteomics and metabolomics of the human vascular endothelial cells at the single cell level will help build a single cell atlas of human vascular endothelium, which would give a unique ID card for each cell type, a three-dimensional map of how cell types work together to form tissues and insights into how changes in the map underlie health and disease of the vascular endothelium from young to old age. Disocver the latest research on the single cell atlas of human vascular endothelial cell atlas here.

Related Papers

American Journal of Physiology. Renal Physiology

PTH transiently increases the percent mobile fraction of Npt2a in OK cells as determined by FRAP

American Journal of Physiology. Renal PhysiologyOctober 2, 2009
E J WeinmanMark Donowitz
Paper Details
References
  • References19
  • Citations13
12
  • References19
  • Citations13
12

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