Dynamics of sister chromatids through the cell cycle: Together and apart

The Journal of Cell Biology
Motoko Takahashi, Toru Hirota

Abstract

When and how sister chromatid resolution occurs after DNA replication is a fundamental question. Stanyte et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201801157) used CRISPR/Cas9 technology to label and track genomic loci in live cells throughout the cell cycle, shedding light on how replication is linked to mitotic sister chromatid organization.

References

Nov 30, 2010·Cell·Tomoko NishiyamaJan-Michael Peters
Feb 13, 2013·The Journal of Cell Biology·Takao OnoTatsuya Hirano
Nov 22, 2013·Molecular Biology of the Cell·Lina Marcela Gallego-PaezToru Hirota
Feb 24, 2016·The EMBO Journal·Rene LadurnerJan-Michael Peters
May 3, 2016·Nature Cell Biology·Kota NagasakaToru Hirota
Oct 7, 2017·Cell·Suhas S P RaoErez Lieberman Aiden
Apr 27, 2018·The Journal of Cell Biology·Rugile StanyteDaniel W Gerlich

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Methods Mentioned

BETA
light microscopy
immunoprecipitation
by

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