PMID: 15224595Jul 1, 2004Paper

Dyschezia in dogs with discrete erosive anal disease and histological lesions suggestive of mucocutaneous lupus erythematosus

The Veterinary Record
E SchrauwenT Maenhout

Abstract

Eight dogs suffered chronic defecation problems characterised by severe dyschezia, manifested by signs of fear and vocalisation on defecation. One or more depigmented, discrete erosions, easily bleeding on palpation, were found in the perineal region. Histopathological changes included interface dermatitis, apoptotic keratinocytes, focal hydropic degeneration of basal epidermal cells, focal thickening of the basement membrane zone and dermal lichenoid infiltrations with mononuclear and plasma cells. A diagnosis of cutaneous or discoid lupus erythematosus was made on the basis of these clinical, physical and specific histopathological changes. The dogs were treated systemically with immunomodulating drugs and good results were obtained.

References

Oct 1, 1989·Journal of the American Academy of Dermatology·P A FantiU Bonelli
Jan 1, 1989·Veterinary Surgery : VS·R A White, N T Gorman
Jan 6, 2001·Critical Reviews in Immunology·M G Scott, R E Hancock

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Citations

Jun 23, 2015·Veterinary Dermatology·Thierry OlivryKeith E Linder
Jul 22, 2005·Journal of Integrative Neuroscience·Andrew H KempLeanne M Williams
Apr 20, 2018·BMC Veterinary Research·Thierry OlivryFrane Banovic

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