PMID: 627621Jan 1, 1978Paper

Dysfibrinogenaemia and liver cell growth

Journal of Clinical Pathology
R D BarrJ L McPhie

Abstract

From the evidence presented, it is proposed that 'dysfibrinogenaemia' represents the production of normal fetal fibrinogen by rapidly proliferating liver cells in both regenerating and neoplastic tissue. Prolongation of the reptilase clotting time, which was formerly believed to reflect dysfibrinogenaemia, may be rather the result of hepatocytic death.

References

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Citations

May 1, 1984·Thrombosis Research·J L FrancisV J Simmonds
Jun 1, 1982·Journal of Clinical Pathology·J L Francis, D J Armstrong
Jan 1, 1981·Critical Reviews in Clinical Laboratory Sciences·D A Triplett

Related Concepts

Blood Coagulation Disorders
Blood Coagulation Tests
Gamma-Fibrinogen
Liver Dysfunction
Malignant Neoplasm of Liver
Liver Regeneration
Reptilase

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