Dyslipidemia and Fatty Liver Disease in Overweight and Obese Children

Journal of Obesity
Asma DeebAbubaker Elfatih

Abstract

Obesity is a worldwide concern. It is associated with morbidity such as dyslipidemia and liver disease. Childhood obesity has dramatically increased, particularly in the Gulf region. We aim to assess the prevalence of dyslipidemia and fatty liver disease (FLD) in overweight and obese children and analyze the association between different anthropometric measures with dyslipidemia and fatty liver disease. A descriptive, cross-sectional study conducted on children referred with obesity. BMI percentiles were plotted and standardized waist circumference (WC) was generated. Family history of metabolic syndrome was recorded. Fasting lipid, liver transaminases, and ultrasound scans (US) for those with elevated enzymes were performed. Descriptive statistics were used for quantitative parameters. 216 participants were recruited. Mean ± SD age was 10.58 ± 2.996 years. 55.3% had dyslipidemia; 11.7% had high cholesterol, 28.6% high triglyceride, 32.7% high LDL, and 18.0% low HDL. 51 (84%) had either elevated transaminases. All had liver US, and 43 had FLD. WC was strongly associated with dyslipidemia and FLD (P=0.04  and  0.003). Dyslipidemia is common in overweight, obese children. FLD is prevalent in those with elevated liver transaminase...Continue Reading

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Citations

Dec 11, 2019·Clinical Chemistry and Laboratory Medicine : CCLM·Olga ScudieroBarbara Lombardo
Feb 26, 2019·Journal of Periodontology·Raissa Silva Bacelar de AndradeDaniel Fernando Pereira Vasconcelos
Aug 21, 2019·Frontiers in Endocrinology·Ebe D'AdamoValerio Nobili
Jul 28, 2020·Italian Journal of Pediatrics·Roberta RomanelliGiuseppina Rosaria Umano
Mar 7, 2021·International Journal of Environmental Research and Public Health·Beata Bondyra-WiśniewskaAnna Harton
Mar 18, 2021·Curēus·Umar FarooqueMuhammad Daim Bin Zafar
Aug 31, 2021·Oxidative Medicine and Cellular Longevity·Pedro BarbosaEugenia Carvalho
Sep 16, 2021·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Deyse M DutraCarolina P Faria
Jan 23, 2022·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Srinivasan ThiagarajanThirunavukkarasu Arun Babu

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Methods Mentioned

BETA
biopsy

Software Mentioned

SPSS

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