PMID: 28528344May 22, 2017Paper

Dysnatremia is an Independent Indicator of Mortality in Hospitalized Patients

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Jiachang HuXiaoqiang Ding

Abstract

BACKGROUND Dysnatremia is a risk factor for poor outcomes. We aimed to describe the prevalence and outcomes of various dysnatremia in hospitalized patients. High-risk patients must be identified to improve the prognosis of dysnatremia. MATERIAL AND METHODS This prospective study included all adult patients admitted consecutively to a university hospital between October 1, 2014 and September 30, 2015. RESULTS All 90 889 patients were included in this study. According to the serum sodium levels during hospitalization, the incidence of hyponatremia and hypernatremia was 16.8% and 1.9%, respectively. Mixed dysnatremia, which was defined when both hyponatremia and hypernatremia happened in the same patient during hospitalization, took place in 0.3% of patients. The incidence of dysnatremia was different in various underlying diseases. Multiple logistic regression analyses showed that all kinds of dysnatremia were independently associated with hospital mortality. The following dysnatremias were strong predictors of hospital mortality: mixed dysnatremia (OR 22.344, 95% CI 15.709-31.783, P=0.000), hypernatremia (OR 13.387, 95% CI 10.642-16.840, P=0.000), and especially hospital-acquired (OR 16.216, 95% CI 12.588-20.888, P=0.000) and pe...Continue Reading

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Citations

Mar 28, 2020·Clinical Journal of the American Society of Nephrology : CJASN·Api ChewcharatKianoush B Kashani
Dec 12, 2018·Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research·Yimei WangXiaoqiang Ding
Sep 19, 2019·Jornal brasileiro de nefrologia : ʹorgão oficial de Sociedades Brasileira e Latino-Americana de Nefrologia·Edward Mezones-HolguinAdrian V Hernandez
Aug 9, 2020·Infection and Drug Resistance·Lidvine GodaertMoustapha Dramé
Feb 12, 2020·Internal Medicine Journal·Cecilia ChiN Wah Cheung
Jul 23, 2019·Kidney & Blood Pressure Research·Gianmarco LombardiGiovanni Gambaro

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