Dyspepsia and disease burden among patients with atrial fibrillation

Critical Pathways in Cardiology
Joyce C LaMoriWinnie W Nelson

Abstract

This retrospective, observational study was conducted to determine overlap of prevalence between atrial fibrillation (AF), an increasingly common condition that primarily affects the elderly population, and dyspepsia, which is also common. Because the overlap of these conditions could interfere with health care including medication selection, the effect on patient outcomes was also evaluated. A demographically representative population of adults in the United States self-administered an Internet-based questionnaire, and responses were evaluated to determine the presence of AF and measures of comorbidity, including CHADS2 score of stroke risk. Health-related quality of life, work productivity and activity impairment, and health care resource utilization were also assessed. The impact of dyspepsia on these patient outcomes was then examined with multiple regressions and generalized linear models. From the sample population, 1297 participants reported being diagnosed with AF, of whom 34% (449/1297) reported diagnosis of dyspepsia. Those with dyspepsia had a higher mean CHADS2 score than those without dyspepsia. Despite this higher risk, significantly fewer AF patients with dyspepsia than those without dyspepsia were taking either ...Continue Reading

References

Oct 4, 2006·Journal of Clinical Gastroenterology·Lauren B GersonGeorge Triadafilopoulos
Oct 10, 2007·Clinics in Geriatric Medicine·Sarah J Crane, Nicholas J Talley

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Citations

Oct 18, 2012·BMC Musculoskeletal Disorders·Jan-Samuel WagnerJoseph C Cappelleri
Nov 14, 2014·SpringerPlus·François LalibertéPatrick Lefebvre
Sep 27, 2014·Journal of Neurogastroenterology and Motility·Yasuhiro Fujiwara, Tetsuo Arakawa

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