Dysphagia as a manifestation of thyrotoxicosis: report of three cases and literature review

Dysphagia
Wei-Yih ChiuTien-Shang Huang

Abstract

Myopathy is frequently associated with thyrotoxicosis. Skeletal muscles are predominantly involved in thyrotoxic myopathy, but dysphagia is extremely rare. We report three cases of thyrotoxicosis with dysphagia and review of the literature of the past 30 years. Most of these patients had antecedent muscle weakness before the onset of dysphagia although some suffered from a sudden onset of bulbar palsy. Either a myopathic or neuropathic pattern was found on electromyography. The incidence of oropharyngeal dysphagia was higher than that of esophageal motility dysfunction. Aspiration pneumonia occurred more accompanied by oropharyngeal dysphagia. The swallowing disorder could be resolved completely within 3 weeks after treatment for thyrotoxicosis. In light of these clinical experiences, early intensive treatment that includes antithyroid agent, beta-blocker, and Lugol solution may be necessary.

Citations

Nov 27, 2008·World Journal of Surgery·David Yü GreenblattHerbert Chen
Feb 15, 2011·Case Reports in Medicine·Konstantinos ParperisVivian Argento
Jun 18, 2009·World Journal of Gastroenterology : WJG·Ronald DaherBassam Abboud
May 24, 2006·World Journal of Gastroenterology : WJG·Christina MaserSanziana Roman
Nov 29, 2020·Muscle & Nerve·Benjamin Claytor, Yuebing Li
Aug 2, 2017·Current Opinion in Otolaryngology & Head and Neck Surgery·Inn-Chul Nam, Young-Hak Park
Apr 12, 2007·Chest·Michael Eberlein, David B Pearse

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