Dysplasia and Cancer in Inflammatory Bowel Disease

The Surgical Clinics of North America
Lyen C Huang, Amit Merchea

Abstract

Inflammatory bowel disease is associated with an increased risk of dysplasia and cancer. Improvements in medical management and endoscopic surveillance have reduced these risks. Patients can develop cancer even in the absence of dysplasia or with indefinite or low-grade dysplasia. Most guidelines recommend starting surveillance colonoscopy 6 to 10 years after initial diagnosis with interval surveillance afterward every 1 to 5 years depending on risk and/or individual characteristics. Most patients should undergo total proctocolectomy with end ileostomy or reconstruction with ileal pouch anal anastomosis because segmental and subtotal resections carry a higher risk of metachronous cancers.

Citations

May 31, 2018·Nature Reviews. Gastroenterology & Hepatology·Patrice D Cani, Benedicte F Jordan
May 10, 2020·Gastroenterology Research and Practice·Xian-Rui WuPing Lan
Jan 8, 2018·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Saurabh KediaUNKNOWN for Indian Society of Gastroenterology Task Force on Inflammatory Bowel Disease
Apr 25, 2020·Case Reports in Gastrointestinal Medicine·Gregorios ChristodoulidisDimitrios Zacharoulis

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