Dysprosium and Holmium Vanadate Nanoprobes as High-Performance Contrast Agents for High-Field Magnetic Resonance and Computed Tomography Imaging.

Inorganic Chemistry
Elisabet Gómez-GónzalezManuel Ocaña

Abstract

We describe a wet chemical method for the synthesis of uniform and well-dispersed dysprosium vanadate (DyVO4) and holmium vanadate (HoVO4) nanoparticles with an almost spherical shape and a mean size of ∼60 nm and their functionalization with poly(acrylic acid). The transverse magnetic relaxivity of both systems at 9.4 T is analyzed on the basis of magnetic susceptibility and magnetization measurements in order to evaluate their potential for application as high-field MRI contrast agents. In addition, the X-ray attenuation properties of these systems are also studied to determine their capabilities as computed tomography contrast agent. Finally, the colloidal stability under physiological pH conditions and the cytotoxicity of the functionalized NPs are also addressed to assess their suitability for bioimaging applications.

References

Oct 19, 2005·Investigative Radiology·Martin RohrerHanns-Joachim Weinmann
Mar 22, 2008·Journal of the American Chemical Society·Małgorzata NorekJoop A Peters
Mar 25, 2011·Advanced Materials·José A BarretoLeone Spiccia
May 24, 2011·Progress in Nuclear Magnetic Resonance Spectroscopy·Małgorzata Norek, Joop A Peters
Sep 14, 2012·Nanoscale·Fengqin Hu, Yong Sheng Zhao
Dec 21, 2012·Quantitative Imaging in Medicine and Surgery·Yi-Xiang J Wang
Jun 19, 2013·Dalton Transactions : an International Journal of Inorganic Chemistry·Nuria O NuñezManuel Ocaña
Feb 16, 2012·The Journal of Physical Chemistry Letters·Gautom Kumar DasFrank C J M van Veggel
Jul 28, 2016·Langmuir : the ACS Journal of Surfaces and Colloids·Darja LisjakMaja Ponikvar-Svet
Aug 28, 2019·Ultrasonics Sonochemistry·Mohammad Hossein KhorasanizadehMasoud Salavati-Niasari

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