Dyssynchrony during acute phase determined by real-time three-dimensional echocardiography predicts reverse cardiac remodeling and improved cardiac function after reperfusion therapy

Journal of cardiology
Yoshiaki MaruyamaNobuo Yoshimoto

Abstract

The aim of this study was to investigate whether parameters of dyssynchrony from real-time three-dimensional echocardiography (RT-3DE) can predict cardiac remodeling in patients of acute myocardial infarction (AMI) after reperfusion therapy. The subjects were 41 AMI patients after reperfusion therapy who underwent RT-3DE within 2 weeks from onset and at 6 months thereafter. End-diastolic volume (EDV), end-systolic volume (ESV), ejection fraction (EF), and the change rate of these parameters were derived during the acute and chronic phases. Two parameters of dyssynchrony, the systolic timing dispersion index (SDII) and systolic timing deviation index (SDEI) were calculated from RT-3DE. Intra- and inter-observer variability of dyssynchrony parameters and correlation of acute cardiac and dyssynchrony parameters with chronic remodeling were compared using linear and multiple regression analysis. Parameters of dyssynchrony from RT-3DE revealed small intra- and inter-observer variability. Acute EDV, acute ESV, and acute EF correlated with chronic remodeling but not with the change rate of these parameters. SDII correlated negatively with chronic remodeling and positively with chronic EF, and the change rate of these parameters. Multi...Continue Reading

References

May 31, 2002·International Journal of Cardiology·Nicholas G BellengerDudley J Pennell
Oct 22, 2003·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Hein J VerberneBerthe L F van Eck-Smit
Feb 6, 2007·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Yves G C J AmericaErnst E van der Wall
Sep 4, 2007·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Sjoerd A MollemaJeroen J Bax
Oct 16, 2007·Journal of the American College of Cardiology·Sjoerd A MollemaJeroen J Bax
Nov 26, 2008·Journal of cardiology·Jun MurakamiMasahiko Kurabayashi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiac Remodeling

Cardiac remodeling in response to a myocardial infarction is characterized by progressive ventricular dilatation, cardiac hypertrophy, fibrosis, and deterioration of cardiac performance. Discover the latest research on Cardiac Remodeling here.