Dysthymic and anxiety-related personality traits in bipolar spectrum illness

Journal of Affective Disorders
J SavitzR Ramesar

Abstract

Anxious and dysthymic personality traits were measured in a euthymic, familial sample of bipolar (BPD) individuals and their affectively ill and unaffected relatives. According to the quantitative genetic model of bipolar spectrum illness [Evans, L., Akiskal, H.S., Keck, Jr., P.E., McElroy, S.L., Sadovnick, A.D., Remick, R.A., Kelsoe, J.R., 2005. Familiality of temperament in bipolar disorder: support for a genetic spectrum. J. Affect. Disord. 85, 153-168], these traits should be normally distributed with the bipolar disorder I (BPD I) group showing the highest and the unaffected relatives the least "pathological" scores. Three hundred individuals from 47 bipolar disorder families were administered a battery of personality questionnaires (Temperament Evaluation of Memphis, Pisa, Paris, and San Diego; Temperament and Character Inventory; Affective Neuroscience Personality Scale) as well as a self-rating depression (Beck Depression Inventory) and mania (Altman Self-Rating Mania) scale. Out of the 300 participants, 58 were diagnosed with BPD I, 27 with bipolar disorder II (BPD II), 58 with recurrent major depression (MDE-R), 45 had one previous depressive episode (MDE-S), and 88 were unaffected. The BPD I group scored significantl...Continue Reading

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May 14, 2003·Archives of General Psychiatry·Anne FarmerPeter McGuffin
Mar 23, 2005·Journal of Affective Disorders·Lynn EvansJohn R Kelsoe
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Aug 2, 2006·Bipolar Disorders·Jonathan B Savitz, Rajkumar S Ramesar
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Citations

Mar 4, 2011·Psychiatric Genetics·Ney Alliey-RodriguezElliot S Gershon
Aug 21, 2013·Computational and Mathematical Methods in Medicine·Tomi KauppiHeikki Kälviäinen
Apr 30, 2011·Neuroscience and Biobehavioral Reviews·Kenneth L Davis, Jaak Panksepp
May 12, 2009·Neuroscience and Biobehavioral Reviews·Jonathan Savitz, Wayne C Drevets
Aug 24, 2010·Comprehensive Psychiatry·Astrid Kristine Kahr NilssonRasmus Wentzer Licht
Jan 1, 2015·Consciousness and Cognition·Donné van der Westhuizen, Mark Solms
Aug 27, 2013·Journal of Affective Disorders·Tiffany A GreenwoodJohn R Kelsoe
Apr 7, 2009·Journal of Affective Disorders·Lorenzo MazzariniEduard Vieta
Feb 2, 2019·Frontiers in Neuroscience·Kenneth L Davis, Christian Montag
Aug 10, 2018·Personality Neuroscience·Christian Montag, Kenneth L Davis

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Bipolar disorder is characterized by manic and/or depressive episodes and associated with uncommon shifts in mood, activity levels, and energy. Discover the latest research this illness here.