Dystopic neurohypophysis

Endocrine Pathology
Faruk Aydin, INitya R Ghatak

Abstract

A dystopic neurohypophysis was noted incidentally at autopsy in a 51 -year-old man with no endocrine abnormality. The dystopic gland was situated in the upper region of the tuber cinereum and macroscopically simulated a neoplasm. The pituitary fossa contained only anterior hypophyseal elements. Review of the literature disclosed 19 such cases discovered at autopsy; 11 occurred in normal individuals with no endocrine abnormality. Radiological study revealed 145 additional cases. Except for the 6 occurrences described in normal individuals, the rest occurred in patients with anterior pituitary dysfunction. No instance of isolated diabetes insipidus has been reported due to dystopia of the neurohypophysis. Dystopia of the neurohypophysis in normal individuals should be distinguished from those occurring in patients with anterior pituitary abnormalities. The former represent a true dystopia and are not associated with perinatal injury, in contrast to the latter, which are acquired dystopias secondary to regeneration of the neurohypophysis and are associated with perinatal injury. Although anterior and posterior pituitary glands are formed by appositional growth, their development and functional status are entirely independent. Fina...Continue Reading

References

Jan 1, 1989·Hormone Research·E A WerderA Valavanis
Aug 1, 1989·AJR. American Journal of Roentgenology·F GudinchetD Lallemand
Oct 1, 1988·The Journal of Clinical Endocrinology and Metabolism·K KikuchiM Sudo
Jan 1, 1988·Anatomy and Embryology·H IkedaH Niizuma
Mar 1, 1987·Journal of Computer Assisted Tomography·I FujisawaY Nakano
Jan 1, 1972·Brain : a Journal of Neurology·P M Daniel, M M Prichard
Oct 1, 1957·The Journal of Pediatrics·R M EHRLICH
Jun 1, 1955·Endocrinology·D C BILLENSTIEN, T F LEVEQUE
Jul 1, 1951·The Journal of Pathology and Bacteriology·B LENNOX, D S RUSSELL

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