E-cadherin expression in canine cutaneous histiocytomas

The Veterinary Record
S J BainesI McConnell

Abstract

Canine cutaneous histiocytoma is a common skin tumour of Langerhans cell origin. Langerhans cells are members of the dendritic cell family of antigen-presenting cells and are located in the epidermis. They are unique among the dendritic cell lineage in that they express high levels of the adhesion molecule E-cadherin. The expression of E-cadherin by the neoplastic Langerhans cells in 37 dogs with cutaneous histiocytoma was studied by flow cytometry and immunohistochemistry. In all the cases, these cells expressed E-cadherin, whereas the infiltrating lymphocytes did not.

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Citations

Jan 3, 2013·Veterinary Immunology and Immunopathology·V QeskaA Beineke
Feb 8, 2011·Clinics in Laboratory Medicine·Leslie C Sharkey, Maxey L Wellman
May 14, 2014·Veterinary Clinical Pathology·Nazaré Pinto da CunhaPaola Roccabianca
Jan 8, 2015·Veterinary Research Communications·Katarzyna Paździor-CzapulaAnna Śmiech
Jan 8, 2014·Veterinary Pathology·P F Moore
Mar 19, 2019·Veterinary and Comparative Oncology·Nguyen V SonHiroyuki Nakayama
Jul 16, 2008·The Veterinary Record·I PiresC S Lopes

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