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E. coli endotoxin shock in the dog; treatment with lidocaine or indomethacin

British Journal of Pharmacology

Oct 1, 1978

J R Fletcher, P W Ramwell

Abstract

1 Dogs treated with lidocaine (1 mg kg-1 h-1) or indomethacin (1.5 mg/kg) before and after an LD60 dose (1 mg/kg) of E. coli endotoxin survived for at least 72 h. 2 Although all dogs in both treated groups survived, only those treated with indomethacin were significantly protected again...read more

Mentioned in this Paper

Alkalescens-Dispar Group
Osmosin
Administration Procedure
Endotoxic Shock
Pharmacologic Substance
Complete Blood Count
Plasma
Lidocaine
Adverse Event Associated With Cardiac Arrhythmia
Indomethacin
Paper Details
References
  • References21
  • Citations23
123
  • References21
  • Citations23
123

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Lidocaine or indomethacin improves survival in baboon endotoxin shock

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E. coli endotoxin shock in the dog; treatment with lidocaine or indomethacin

British Journal of Pharmacology

Oct 1, 1978

J R Fletcher, P W Ramwell

PMID: 361135

DOI: 10.1111/j.1476-5381.1978.tb17288.x

Abstract

1 Dogs treated with lidocaine (1 mg kg-1 h-1) or indomethacin (1.5 mg/kg) before and after an LD60 dose (1 mg/kg) of E. coli endotoxin survived for at least 72 h. 2 Although all dogs in both treated groups survived, only those treated with indomethacin were significantly protected again...read more

Mentioned in this Paper

Alkalescens-Dispar Group
Osmosin
Administration Procedure
Endotoxic Shock
Pharmacologic Substance
Complete Blood Count
Plasma
Lidocaine
Adverse Event Associated With Cardiac Arrhythmia
Indomethacin

Feeds With Similar Papers

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

Heart Rhythm & Arrythmias

Heart arrhythmias, also known as irregular heartbeat or cardiac dysrhythmia, are a group of conditions where the heartbeat is irregular (dysrhythmia), too slow (bradycardia), or too fast (tachycardia). Discover the latest research on heart rhythm and arrythmias here.

Related Papers

The Journal of Surgical Research

Lidocaine or indomethacin improves survival in baboon endotoxin shock

The Journal of Surgical ResearchMarch 1, 1978
J R Fletcher, P W Ramwell
Paper Details
References
  • References21
  • Citations23
123
  • References21
  • Citations23
123

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