Early acetabular cartilage wear following hemiarthroplasty: An ovine model

Veterinary and Comparative Orthopaedics and Traumatology : V.C.O.T
John R FieldDonald W Howie

Abstract

Hemiarthroplasty induces degenerative changes in the hip joint, which are difficult to evaluate in vivo. Radiostereometric analysis (RSA) is a radiographic measurement technique that has recently been used to measure acetabular cartilage wear in vivo. The aim of the study was to measure acetabular cartilage wear, using this technique, in an ovine model during the first 14 weeks post-implantation. Measurements of three-dimensional femoral head migration, combined with visual assessments at necropsy and safranin O staining for cartilage integrity, were undertaken. Mean femoral head migration during the first six weeks was 0.525 mm in the medial, 0.144 mm in the cranial, and 0.517 mm in the dorsal direction. The majority of this migration was confirmed to be cartilage wear in the medial and dorsal aspects of the acetabulum at necropsy and with subsequent histological evaluation depicting significant cartilage degeneration. Radiostereometric analysis is the current gold standard technique for in vivo assessment of implant migration following total hip replacement. This study has utilized RSA to quantify the amount of early cartilage wear in vivo, which was supported by ex vivo evaluations. Accurately measuring the amount of cartila...Continue Reading

References

Mar 1, 1989·The Journal of Bone and Joint Surgery. British Volume·S D CookM A Kester
Aug 1, 1984·The Journal of Bone and Joint Surgery. British Volume·R L CruessG T Dang
Jun 1, 1995·The Journal of Bone and Joint Surgery. American Volume·P G DalldorfV D Pellegrini
Mar 14, 1998·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·E R ValstarP M Rozing
Jan 26, 1999·Clinical Orthopaedics and Related Research·S A BrumbyN S Nawana
Aug 10, 2002·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Marjolein C H van der MeulenStuart B Goodman
Aug 10, 2002·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Charles R BragdonWilliam H Harris
Jan 8, 2005·Clinics in Sports Medicine·Andrew D PearleScott A Rodeo
Jul 2, 2005·Journal of Biomechanics·Niclas BörlinCharles R Bragdon
Aug 2, 2005·Clinical Orthopaedics and Related Research·Keith P MinihaneDale R Sumner
Jul 11, 2006·Clinical Orthopaedics and Related Research·Johan KärrholmEdward R Valstar
Oct 31, 2008·Yonsei Medical Journal·Kyoung Ho MoonMan Hee Won
Mar 18, 2009·Veterinary and Comparative Orthopaedics and Traumatology : V.C.O.T·J R FieldK Nilsson

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