Early acid-base balance disorders during kidney transplantation

Transplantation Proceedings
K TejchmanK Ciechanowski

Abstract

Reperfusion is a crucial moment in kidney transplantation. Resumption of blood flow is associated with many metabolic changes, which result from the kidney's initial condition and preservation. These biochemical alterations including the acid-base balance are the part of ischemia-reperfusion injury. The study's purpose was to examine acid-base balance during the first 30 minutes after reperfusion of the transplanted kidney. The 30 recipients (13 men, 17 women) averaged ages of 46 +/- 14 years. Measurements performed nine times (at 0, 1, 3, 5, 10, 15, 20, 25, and 30 minutes after unclamping renal vessels) included: gas analysis, expiratory Pco(2), tidal volume, and respiratory rate. The evaluation of the temporary acid-base balance was performed on the basis of common parameters: pH, Pco(2), [HCO(3)(-)], and base excess (BE). The patients were under general anesthesia with stable external conditions of O(2) saturation, heart rate, blood pressure, and temperature. Blood samples were analyzed using Corning 278 and 248 blood gas analyzer; vital parameters were recorded using Ohmeda 5250 RGM and Dräger Sulla 909V/Julian apparatus. The analysis showed increasing metabolic acidosis with coexisting increase in blood Pco(2), changes tha...Continue Reading

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Citations

Oct 7, 2008·The Journal of Obstetrics and Gynaecology Research·Pernilla Dahm-KählerMats Brännström
Apr 28, 2011·Transplant International : Official Journal of the European Society for Organ Transplantation·Thomas W L ScheerenOliver W Hakenberg
Aug 12, 2020·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Tomić AleksandarMarjanović Ivan
Jun 23, 2018·Jornal Vascular Brasileiro·Cesar Roberto BusatoWillman Josviak

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