Early adenocarcinoma of the uterine cervix

Gynecologic Oncology
T. KakuH Nakano

Abstract

The purpose of this study was to evaluate the prognostic significance of the tumor depth, horizontal spread, and volume in early cervical adenocarcinoma while excluding adenocarcinoma in situ. Thirty cases who had been treated at our institution having cervical adenocarcinoma with a tumor depth of less than 5 mm were clinicopathologically reviewed. The volumes were estimated based on the portion with the largest tumor surface area by multiplying three dimensions: depth, horizontal spread, and a third dimension. The third dimension was calculated by the method of Burghardt to be 1.5 times the largest measured depth or spread. Two of the 30 patients recurred in the vagina at 18 and 163 months after the initial operation; the former patient died of disease 87 months postoperatively. The remaining 28 patients are all doing well without recurrence (range of follow-up from 24 to 232 months; median 79 months). No pelvic or paraaortic lymph node metastases were seen in 25 and 22 cases, respectively. None of the 21 cases with a lesion measuring less than 3 mm in depth had recurrence. On the other hand, 1 of 23 with a tumor volume up to 500 mm3 had recurrence. The estimated 5-year progression-free survival rates for patients with cervica...Continue Reading

Citations

Mar 21, 2001·Cytopathology : Official Journal of the British Society for Clinical Cytology·A HerbertJ A Smith
Feb 7, 2004·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·J BalegaK Y Look
Jul 15, 2005·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·A A El-GhobashyC S Herrington
Mar 1, 2003·Journal of Clinical Pathology·W G McCluggage
Apr 1, 2014·Archives of Pathology & Laboratory Medicine·Joana Loureiro, Esther Oliva
Oct 17, 2013·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·L Hermis MattiE Walker
Mar 12, 2003·BJOG : an International Journal of Obstetrics and Gynaecology·Yasuo HiraiKatsuhiko Hasumi
Nov 24, 2005·Cytopathology : Official Journal of the British Society for Clinical Cytology·T KakuH Nakano
Apr 26, 2002·Gynecologic Oncology·Harriet O SmithCharles R Key
Apr 26, 2002·Gynecologic Oncology·Takahiro KasamatsuKazuo Ohmi
Feb 19, 2000·The Journal of Obstetrics and Gynaecology Research·P L CheahV Sivanesaratnam
Jan 19, 2000·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·A G Ostör
Oct 23, 2010·Obstetrics and Gynecology·Evelyn A ReynoldsWilliam A Cliby
Sep 8, 2011·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Astrid BaalbergenTheo J M Helmerhorst
Feb 28, 2015·The American Journal of Surgical Pathology·Andres A RomaElvio G Silva

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