Early adolescent aggression predicts antisocial personality disorder in young adults: a population-based study

European Child & Adolescent Psychiatry
Alyce M WhippEero Vuoksimaa

Abstract

Modestly prevalent in the general population (~ 4%), but highly prevalent in prison populations (> 40%), the diagnosis of antisocial personality disorder (ASPD) involves aggression as one of several possible criteria. Using multiple informants, we aimed to determine if general aggression, as well as direct and indirect subtypes, assessed in early adolescence (ages 12, 14) predict young adulthood ASPD in a population-based sample. Using data from a Finnish population-based longitudinal twin cohort study with psychiatric interviews available at age 22 (N = 1347), we obtained DSM-IV-based ASPD diagnoses. Aggression measures from ages 12 (parental and teacher ratings) and 14 (teacher, self, and co-twin ratings) were used to calculate odds ratios (OR) of ASPD from logistic regression models and the area under the curve (AUC) from receiver operating characteristic curve analysis. Analyses were adjusted for sex, age, and family structure. All informants' aggression ratings were significant (p < 0.05) predictors of ASPD (OR range 1.3-1.8; AUC range 0.65-0.72). Correlations between informants ranged from 0.13 to 0.33. Models including two or more aggression ratings, particularly age 14 teacher and self ratings, more accurately predicted...Continue Reading

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Citations

Oct 24, 2019·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Richard J RoseJaakko Kaprio
Jan 18, 2020·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Justin M LuninghamGitta H Lubke
Mar 7, 2020·PloS One·Jacinto AzevedoMargarida Figueiredo-Braga
Mar 14, 2021·Scientific Reports·A M WhippJ Kaprio
Apr 15, 2021·Child and Adolescent Psychiatry and Mental Health·Ziyi ZhaoXu Li
Aug 1, 2021·Translational Psychiatry·Hill F IpDorret I Boomsma
Aug 8, 2021·Neuroscience and Biobehavioral Reviews·Melissa MulraneyHarriet Hiscock

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