PMID: 8710766Dec 1, 1995Paper

Early amniocentesis: a clinical review

Prenatal Diagnosis
R D Wilson

Abstract

Early amniocentesis at less than 14 weeks gestation is becoming more common in prenatal diagnosis populations. Randomized studies are minimal and have not had the power to determine the accuracy and safety of the procedure compared to chorionic villus sampling or mid-trimester amniocentesis. Procedures at 11+0-12+6 weeks should be considered experimental. This clinical review considers the ethics, embryology, and clinical experience (cytogenetics, AFP, AChE, procedure and cytogenetic failures, spontaneous and therapeutic pregnancy losses, congenital anomalies) of early amniocentesis.

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Citations

Apr 5, 2008·Current Opinion in Obstetrics & Gynecology·Mark I Evans, Stephanie Andriole
May 24, 2015·Obstetrics and Gynecology Clinics of North America·Mark I EvansShara M Evans
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Jan 12, 1999·British Journal of Obstetrics and Gynaecology·W E Mackenzie, M P Wyldes
Aug 30, 2021·Advanced Drug Delivery Reviews·Anjali SharmaRangaramanujam M Kannan

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