Early assessment of coronary flow reserve by transthoracic Doppler echocardiography predicts late remodeling in reperfused anterior myocardial infarction

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
Fausto RigoEugenio Picano

Abstract

Microvascular integrity is an essential determinant of favorable late outcome in reperfused myocardial infarction. Coronary flow reserve (CFR) can be assessed by transthoracic Doppler echocardiography and provides a functional estimate of microvascular integrity downstream from the patent infarct-related vessel. We sought to assess the effects of CFR in predicting late left ventricular (LV) remodeling in patients with reperfused acute anterior myocardial infarction treated with primary angioplasty. In all, 31 patients admitted with acute anterior myocardial infarction underwent primary angioplasty of the infarct-related vessel. After angioplasty, angiographic thrombosis in myocardial infarction (TIMI) grade and myocardial blush were scored. On the first day, all underwent stress echocardiography and CFR evaluation of left anterior descending coronary artery by transthoracic Doppler. All patients had resting 2-dimensional echocardiography at 1, 3, and 6 months for assessment of LV function. CFR could be successfully assessed in 31 patients. After 6 months 5 patients showed LV dilatation (group I), whereas 26 patients did not show significant variation (group II). On day 1, CFR was higher (group I = 1.43 +/- 0.11 vs group II = 1....Continue Reading

References

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Citations

Apr 2, 2011·Journal of Cardiovascular Translational Research·Parham EshtehardiHabib Samady
Sep 25, 2012·European Heart Journal Cardiovascular Imaging·Patrick MeimounAnne Luycx-Bore
Nov 15, 2011·European Heart Journal Cardiovascular Imaging·Lauro CortigianiRosa Sicari
Jun 28, 2006·Journal of Cardiovascular Medicine·Fausto RigoLauro Cortigiani
Jun 15, 2007·Journal of Cardiovascular Medicine·Silvia FavilliRoberta M Bini
Aug 12, 2014·The International Journal of Cardiovascular Imaging·Danijela TrifunovicMiodrag Ostojic
Aug 21, 2012·Trends in Cardiovascular Medicine·William HiesingerY Joseph Woo
Apr 26, 2011·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Ana Djordjevic-DikicMiodrag Ostojic
Aug 4, 2009·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Patrick MeimounChristophe Tribouilloy
Apr 10, 2010·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Patrick MeimounChristophe Tribouilloy
Feb 26, 2008·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Patrick Meimoun, Christophe Tribouilloy
Feb 22, 2017·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Mariëlla E C J HassellJan J Piek

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