PMID: 9631217Jun 19, 1998Paper

Early assessment of exercise induced skeletal muscle injury using plasma fatty acid binding protein

British Journal of Sports Medicine
S SorichterJ F Glatz

Abstract

To test whether fatty acid binding protein (FABP) is a useful plasma marker for the early detection of exercise induced skeletal muscle injury in healthy subjects. Plasma concentrations of FABP and myoglobin (Mb) were measured in six healthy physical education teacher trainees after 20 minutes of downhill running (16% incline; mean lactate 4 mmol/l; 70% (VO2MAX). Creatine kinase (CK) was measured for comparison. Significant increases were found in plasma FABP (mean peak level 50 micrograms/l), Mb (823 micrograms/l), and CK (491 U/l). Mb and FABP concentrations were already significantly elevated (p < 0.05) at 30 minutes, but CK not until two hours after exercise. Whereas Mb and FABP decreased to normal levels within 24 hours, CK activity remained elevated until 48 hours. The Mb to FABP ratio in plasma after exercise induced muscle injury was 15.0 (1.3) (mean (SEM)) (range 7.4-31.1), which is within the range of ratios calculated for skeletal muscle tissue contents of Mb and FABP, but different from the reported plasma ratio after myocardial injury (4-6). After eccentric exercise induced muscle injury, plasma FABP and Mb increase and decrease more rapidly than CK, indicating that both FABP and Mb are more useful than CK for the ...Continue Reading

References

Oct 21, 1992·Molecular and Cellular Biochemistry·A H KleineG J Van der Vusse
May 1, 1992·Medicine and Science in Sports and Exercise·P M ClarksonB Braun
Jul 1, 1990·Journal of Neurology·M F Driessen-KletterJ van Gijn
Jun 14, 1995·Journal of Immunological Methods·W RoosJ F Glatz
Jun 1, 1993·Journal of Applied Physiology·J B RodenburgR W De Boer
Dec 10, 1997·International Journal of Sports Medicine·P M Clarkson

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Sep 27, 2003·Research Quarterly for Exercise and Sport·Yvonne YuanReinhard Renneberg
Dec 25, 2010·Computer Methods in Biomechanics and Biomedical Engineering·Yael Ruschkewitz, Amit Gefen
Mar 19, 2004·QJM : Monthly Journal of the Association of Physicians·H A Alhadi, K A A Fox
Nov 29, 2005·Clinical Chemistry and Laboratory Medicine : CCLM·Dirk PeetzKarl J Lackner
Aug 25, 2010·Journal of Strength and Conditioning Research·Lisa Ferguson-StegallJohn L Ivy
Apr 15, 2010·Journal of Immunoassay & Immunochemistry·Pei-Yi XieReinhard Renneberg
Dec 20, 2013·Expert Review of Proteomics·Dayle L SampsonTony J Parker
Jun 17, 2010·American Journal of Clinical Pathology·Yeongsic KimByung Hak So
Nov 26, 2010·PM & R : the Journal of Injury, Function, and Rehabilitation·Mohsen MakhsousChristopher C Chadwick
Nov 11, 2008·Clinica Chimica Acta; International Journal of Clinical Chemistry·Tuomo IlvaKari Pulkki
Jan 18, 2005·Clinica Chimica Acta; International Journal of Clinical Chemistry·Maurice M A L PelsersJan F C Glatz
Feb 24, 2006·The American Journal of Emergency Medicine·Jamal A Alhashemi
Apr 7, 2015·Journal of Athletic Training·John P VardimanPhilip Gallagher
Jul 19, 2008·Clinical Chemistry and Laboratory Medicine : CCLM·Giuseppe LippiGian Cesare Guidi
Feb 20, 2015·European Journal of Applied Physiology·Clare MinahanSurendran Sabapathy
Dec 16, 2011·Journal of the International Society of Sports Nutrition·Claudia R da LuzAntonio H Lancha
Mar 30, 2016·Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Für Toxikologische Pathologie·Karen BodiéAndreas Popp
Mar 19, 2011·Journal of Proteomics·Cecilia GelfiPaolo Cerretelli
Mar 1, 2008·Toxicological Sciences : an Official Journal of the Society of Toxicology·Michael L PrittDavid E Watson
Sep 2, 2008·Journal of Orthopaedic Trauma·Babak ShadganW Darlene Reid
Sep 3, 2018·Clinical Chemistry and Laboratory Medicine : CCLM·Giuseppe LippiFerruccio Ceriotti
Dec 30, 2018·Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research·Michael SponderJeanette Strametz-Juranek
Jan 15, 2002·American Journal of Physiology. Endocrinology and Metabolism·Jeff S VolekPaula Gaynor
Dec 13, 2016·Journal of Strength and Conditioning Research·Michael BehringerJoachim Mester
Oct 17, 2012·International Journal of Sports Physiology and Performance·Paul G Montgomery, Will G Hopkins
Apr 5, 2002·Medicine and Science in Sports and Exercise·Robert ShaveDavid Gaze
Oct 11, 2020·Sports Medicine·Bastien BontempsJulien Louis

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