Early bladder cancer: concept, diagnosis, and management

International Journal of Clinical Oncology
Hiroshi Kitamura, Taiji Tsukamoto

Abstract

Recent evidence on molecular pathways helps us to understand the pathogenesis of bladder cancer. However, the molecular mechanisms of recurrence of the disease and progression into muscle-invasive disease are not fully understood. The diagnostic accuracy and specificity of innovative markers for detection of the disease currently available in the clinical setting are still far from the level where cystoscopy would not be needed. Although risk factors for progression to muscle-invasive disease have been identified, we still cannot predict accurately the clinical behavior of superficial bladder cancer. In this review article, we summarize recent evidence on molecular pathogenesis, risk factors for recurrence and progression, urine markers for detection, and treatments in superficial bladder cancer.

References

Mar 12, 1992·The New England Journal of Medicine·D SidranskyB Vogelstein
Mar 12, 1992·The New England Journal of Medicine·A L Harris, D E Neal
Jan 1, 1986·Scandinavian Journal of Urology and Nephrology·H O Beisland, P Seland
Dec 1, 1983·The Journal of Urology·N M HeneyI R Hawkins
Feb 26, 1993·Science·M Hoffman
Aug 1, 1997·Nature Medicine·G AmbrosiniD C Altieri
Jul 1, 1997·Journal of Internal Medicine·J R FraserU B Laurent
Nov 20, 1997·The Journal of Urology·B JohnstonM Lundie
Oct 31, 1998·International Journal of Cancer. Journal International Du Cancer·M ShigyoT Kakizoe
May 21, 1999·Lancet·A B AlexandroffK James
Jul 8, 1999·The American Journal of Pathology·I OrlowC Cordon-Cardo
Nov 27, 1999·European Urology·P RischmannD K Chopin
Mar 4, 2000·The Urologic Clinics of North America·J Tsihlias, H B Grossman
Mar 4, 2000·The Urologic Clinics of North America·V B Lokeshwar, N L Block
Mar 4, 2000·The Urologic Clinics of North America·B C Liu, K R Loughlin
Apr 18, 2000·Emergency Medicine Clinics of North America·R Olmedo, R S Hoffman
Feb 15, 2001·International Journal of Cancer. Journal International Du Cancer·M KinoshitaH Mochizuki
Feb 15, 2001·JAMA : the Journal of the American Medical Association·S D SmithD C Altieri
Mar 10, 2001·The American Journal of Pathology·A RistimäkiC Haglund
Jun 8, 2001·Journal of Endourology·P K Pietrow, J A Smith
Jun 8, 2001·The American Journal of Pathology·C BillereyF Radvanyi
Jun 9, 2001·Endocrine-related Cancer·L R HoweA J Dannenberg
Aug 21, 2001·Journal of Insurance Medicine·M Moore
Jan 31, 2002·Annual Review of Medicine·Marco E Turini, Raymond N DuBois
Feb 7, 2002·Urological Research·P Jichlinski, H J Leisinger
Sep 5, 2002·International Journal of Cancer. Journal International Du Cancer·Christian HafnerArndt Hartmann
Feb 11, 2003·The Journal of Urology·Christian PfisterJean-Jacques Rambeaud

❮ Previous
Next ❯

Citations

Sep 18, 2009·The Journal of Urology·Cecilia A FernándezAnthony P Shuber
Oct 13, 2009·International Journal of Cancer. Journal International Du Cancer·Paola GazzanigaMassimo Cristofanilli
Sep 13, 2012·Biochimica Et Biophysica Acta·Jian ZhangDaniel Raftery
Jul 5, 2008·Expert Review of Molecular Diagnostics·Aza MohammedLeslie Gilliland
Apr 7, 2007·Current Opinion in Oncology·Peter E Clark
Apr 9, 2008·Current Opinion in Oncology·Daniel A Barocas, Peter E Clark
Feb 5, 2010·BJU International·Angela GradilonePaola Gazzaniga
Dec 20, 2007·Expert Review of Molecular Diagnostics·Aza MohammedAftab Bhatti
Aug 11, 2006·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Hiroshi KitamuraTaiji Tsukamoto
Jun 18, 2011·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Sanaa EissaOmar El-Ahmady
Jan 19, 2021·Journal of Oral and Maxillofacial Pathology : JOMFP·J GowthamiDaffney Mano Doss
Mar 27, 2010·Journal of Proteome Research·Kishore Kumar PasikantiEric Chun Yong Chan
Nov 14, 2013·Journal of Proteome Research·Navneeta BansalSudhir Kumar Mandal

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Nature Reviews. Urology
Anirban P Mitra, Richard J Cote
Lancet
Donald S KaufmanAdam S Feldman
Archivos españoles de urología
F J Fernández Mena, Y C Moreno-Torres
© 2021 Meta ULC. All rights reserved