PMID: 9633498Jun 20, 1998Paper

Early carotid endarterectomy after non-disabling ischaemic stroke: adequate therapeutical option in selected patients

European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery
H H EcksteinJ Allenberg

Abstract

To evaluate neurological outcome and long-term results of early carotid endarterectomy (CEA) after non-disabling stroke. Retrospective study between 1980 and 1995 of 56 patients undergoing CEA within 4 weeks of a transient (n = 15) or a permanent non-disabling (n = 41) ischaemic stroke. Analyses of preoperative cerebral CT imaging, neurological outcome (mod. Rankin-scale) and long-term results (life-table analyses according to Kaplan-Meier). Incidence of early CEA increased from 1.7% (27 out of 1636) in the period 1980-1993 to 7.8% (29 out of 374) between 1994 and 1995. CEA was indicated after a neurological plateau phase was established (median interval 14 days). Fifty-seven per cent of the CEA patients had a minor ischaemic infarction (area < 2 cm), 18% showed a large territorial ischaemic infarction (area 2-5 cm) in cerebral CT imaging. Two patients deteriorated postoperatively (minor stroke rate 4%) but no major stroke or death occurred. Life-table probability of stroke-free survival (mean follow-up 42.7 months) was 94%, 90% and 84%, respectively, after 1, 2 and 5 years. Kaplan-Meier survival rates were 96%, 91% and 86% after 1, 2 and 5 years. Early CEA after non-disabling stroke is a safe procedure in selected patients.

References

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Citations

May 17, 2005·Nitric Oxide : Biology and Chemistry·Karsten HemmrichVictoria Kolb-Bachofen
May 14, 1999·Pharmaceutical Science & Technology Today·A L Daugherty, R J Mrsny
Jul 27, 2004·Cerebrovascular Diseases·S WelshC N McCollum
Apr 5, 2003·Stroke; a Journal of Cerebral Circulation·Harold P AdamsUNKNOWN Stroke Council of the American Stroke Association

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