Early Cervical Cancer: Predictive Relevance of Preoperative 3-Tesla Multiparametric Magnetic Resonance Imaging

International Journal of Surgical Oncology
Hyun Jin RohSang Hun Lee

Abstract

We assess the predictive significance of preoperative 3-Tesla multiparametric MRI findings. A total of 260 patients with FIGO IA2-IIA cervical cancer underwent primary surgical treatment between 2007 and 2016. Univariable and multivariable logistic regression analyses were used to assess the incremental prognostic significance. The clinical predictive factors associated with pT2b disease were MRI parametrial invasion (PMI) (adjusted odds ratio (AOR) 3.77, 95% confidence interval(CI) 1.62-8.79; P=0.02) and MRI uterine corpus invasion (UCI) (AOR 9.99, 95% CI 4.11-24.32; P<0.0001). In multivariable analysis, for underdiagnoses, histologically squamous carcinoma versus adenocarcinoma and adenosquamous carcinoma (AOR 2.07, 95% CI 1.06-4.07; P=0.034) and MRI tumor size (AOR 0.76, 95% CI 0.63-0.92; P=0.005) were significant predictors; for overdiagnoses, these results were MRI tumor size (AOR 1.51, 95% CI 1.06-2.16; P=0.023), MRI PMI (AOR 71.73, 95% CI 8.89-611.38; P<0.0001) and MRI UCI (AOR 0.19, 95% CI 0.01-1.01; P=0.051). PMI and UCI on T2-weighted images through preoperative 3T MRI are useful coefficients for accurate prediction of the pT2b stage; however, careful surveillance is required. Therefore, preoperative decision-making f...Continue Reading

References

Sep 11, 1975·Clinical Obstetrics and Gynecology·H E AveretteM H Lutz
Jun 1, 1991·AJR. American Journal of Roentgenology·H H LienO Kaalhus
Apr 1, 1989·Radiology·K TogashiI Konishi
Dec 1, 1988·Baillière's Clinical Obstetrics and Gynaecology·H M HofmannE Burghardt
Aug 1, 1971·American Journal of Obstetrics and Gynecology·J R Van NagellD M Lowin
Apr 15, 1999·The New England Journal of Medicine·P G RoseS Insalaco
Oct 7, 2003·American Journal of Clinical Oncology·Kailash NarayanDavid Bernshaw
Dec 15, 2005·The British Journal of Radiology·A JenaK K Pandey
Dec 20, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Hedvig HricakUNKNOWN Gynecologic Oncology Group 183
May 10, 2006·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·K NarayanD Bernshaw
Oct 5, 2015·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Lynette Denny, Michael Quinn

❮ Previous
Next ❯

Citations

Jul 17, 2019·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Radovan VojtíšekJindřich Fínek
Aug 28, 2021·Cancers·Byung Kwan Park, Tae-Joong Kim

❮ Previous
Next ❯

Methods Mentioned

BETA
hysterectomy
biopsy
dissection

Software Mentioned

SPSS

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.