Early characteristics of fulminant myocarditis vs non-fulminant myocarditis: A meta-analysis

Medicine
Zicheng WangDa Gao

Abstract

Fulminant myocarditis (FM) is a sub-category myocarditis. Its primary characteristic is a rapidly progressive clinical course that necessitates hemodynamic support. FM can be difficult to predict at the onset of myocarditis. The aim of this meta-analysis was to identify the early characteristics in FM compared to those of non-fulminant myocarditis (NFM). We searched the databases of MEDLINE, EMBASE, CENTRAL, for studies comparing FM with acute NFM from January 1, 2000 to June 1, 2018. The baseline variables were compared in each study. Mean differences (MD) and relative ratios (RR) were calculated. Seven studies (158 FM patients and 388 NFM patients) were included in the analysis. The FM group had significantly lower systolic blood pressure (SBP), higher creatine kinase (CK), wider QRS duration, lower left ventricular ejection fraction (LVEF), thicker left ventricular posterior wall diameter (LVPWd), higher incidence of ST depression, ventricular tachycardia/ventricular fibrillation (Vt/Vf) and syncope, less incidence of chest pain than the NFM groups. There was no difference in terms of heart rate (HR), c-reactive protein (CRP), fever, dyspnea, white blood cells (WBC), atrioventricular block (AVB), Q waves, ST elevation, inter...Continue Reading

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Citations

Sep 8, 2020·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Nikolaos KosmasEfstathios K Iliodromitis
Nov 30, 2019·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Carmelo ButtàMarco Roberto
Feb 13, 2020·World Journal of Clinical Cases·Tie-Duo KangWen-Xian Liu
Dec 18, 2020·Journal of Cardiac Surgery·Eric I JengMark S Bleiweis
Dec 12, 2020·Signal Transduction and Targeted Therapy·Weijian HangDao Wen Wang
Jun 11, 2021·The Journal of Emergency Medicine·Michael GottliebBrit Long

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