Early Childhood Vaccination Status of Preterm Infants

Pediatrics
Annika M HofstetterJanet A Englund

Abstract

Preterm infants are at increased risk for vaccine-preventable infections and associated complications. Limited studies describe timely vaccination of these vulnerable infants. This retrospective cohort study included Washington State infants with birth hospitalizations at an urban academic medical center between 2008 and 2013. Demographic, clinical, and visit data from electronic health records were linked to vaccine data from the Washington State Immunization Information System. Completion of the recommended 7-vaccine series by 19 months of age was compared between preterm infants (born at <37 weeks' gestation) and term/postterm infants (born at 37-43 weeks' gestation) by using Pearson's χ2 test and multivariable logistic regression. Secondary outcomes included 7-vaccine series completion by 36 months of age and receipt of individual vaccines in the series. Rotavirus, hepatitis A, and influenza vaccination was also assessed. Of study infants (n = 10 367), 19.3% were born prematurely. Preterm infants had lower 7-vaccine series completion compared with term/postterm infants by 19 months (47.5% vs 54.0%; adjusted odds ratio 0.77 [95% confidence interval 0.65-0.90]) and 36 months (63.6% vs 71.3%; adjusted odds ratio 0.73 [95% conf...Continue Reading

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Citations

Dec 19, 2019·Current Opinion in Pediatrics·Mélanie SicardCaroline Quach
Apr 25, 2020·Advances in Neonatal Care : Official Journal of the National Association of Neonatal Nurses·Janelle L B MacintoshRenea Beckstrand
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Feb 19, 2021·Human Vaccines & Immunotherapeutics·Santosh SoansAshish Agrawal
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Aug 18, 2021·Journal of the Pediatric Infectious Diseases Society·Natalia V OsterAnnika M Hofstetter
Dec 4, 2021·Human Vaccines & Immunotherapeutics·Akgün YeşiltepeSemra Bulbuloglu

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