"Early death" and the contraindication of vaccine during treatment of rabies

Vaccine
Rodney E Willoughby

Abstract

Administration of rabies vaccine or rabies immune globulin (RIG) during symptomatic rabies is ineffective, and there are concerns about the phenomenon of "early death" reported in animals that develop rabies after receipt of rabies vaccine or immune globulin. Survival analyses of the original animal data confirm these findings in two species, whereas analyses of human case reports and the Milwaukee Protocol registry suggest lower risk of "early death" in humans. There may be a deleterious interaction of rabies vaccine and RIG with bat rabies in humans. Animal studies of bat rabies virus with bat-origin vaccines and RIG are urgently needed.

References

Jul 1, 1976·Annals of Internal Medicine·C PorrasJ Furst
May 1, 1972·The Journal of Infectious Diseases·G M Baer, W F Cleary
Apr 16, 1981·Nature·B S Prabhakar, N Nathanson
Sep 1, 1981·The Journal of General Virology·B S PrabhakarN Nathanson
Dec 1, 1994·The Pediatric Infectious Disease Journal·L AlvarezG M Baer
Jul 18, 2002·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·S N MadhusudanaM Verendra Kumar
Dec 20, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Alan C JacksonHenry Wilde
Apr 30, 2003·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Thiravat HemachudhaHenry Wilde
May 31, 2003·Nature Reviews. Immunology·Diane E Griffin
Jun 17, 2005·The New England Journal of Medicine·Rodney E WilloughbyCharles E Rupprecht
Sep 13, 2005·Lancet·Monique Lafon
Jul 25, 2006·Nature Medicine·Amin MoghaddamPeter J M Openshaw
May 20, 2008·Transactions of the Royal Society of Tropical Medicine and Hygiene·Henry WildeAlan C Jackson
Jul 8, 2009·Proceedings of the National Academy of Sciences of the United States of America·Milosz FaberBernhard Dietzschold

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Citations

Nov 21, 2012·Journal of Proteome Research·Aifric O'SullivanCarolyn M Slupsky
Sep 2, 2011·Journal of the American Veterinary Medical Association·Catherine M BrownBen Sun
Jun 1, 2013·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Sean J UdowAlan C Jackson
Feb 18, 2016·Journal of the American Veterinary Medical Association·UNKNOWN National Association of State Public Health VeterinariansFaye E Sorhage
Jul 17, 2015·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Mahmoud SadeghiMohammad Montazeri
Aug 23, 2016·Viruses·Terence P Scott, Louis H Nel
Nov 12, 2020·Revista Da Sociedade Brasileira De Medicina Tropical·Leandro Augusto LedesmaMarco Aurélio Horta
Mar 5, 2014·Pediatrics·Joshua R FrancisAdrian C Mattke
May 1, 2012·The Lancet Infectious Diseases·Leonard BothAnthony R Fooks

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