PMID: 8444993Feb 1, 1993Paper

Early dentine lead levels and subsequent cognitive and behavioural development

Journal of Child Psychology and Psychiatry, and Allied Disciplines
D M FergussonM T Lynskey

Abstract

While a number of studies have reported associations between lead levels and cognitive development and behaviour in cross-sectionally studied child samples, there have been relatively few studies of the long term effects of early lead exposure. This issue was studied in a birth cohort of 1265 New Zealand children who were assessed with respect to: (a) dentine lead levels at ages 6-8 years; (b) cognitive and behavioural outcomes at 12, 13 years; (c) various confounding factors. The results of the analysis show: (a) the presence of small but consistent bivariate associations (ranging in absolute size from r = .08 to .20) between early lead levels and later school performance and behaviour; (b) after adjustment for both errors of measurement in test scores and lead levels and adjustment for confounding factors these correlations reduced to between .07 and .14. Nonetheless these correlations remained statistically significant. The evidence is consistent with the view that early mildly elevated lead levels are associated with small but relatively long term deficits in cognitive ability and attentional behaviours.

References

Mar 29, 1979·The New England Journal of Medicine·H L NeedlemanP Barrett
Feb 2, 1990·JAMA : the Journal of the American Medical Association·H L Needleman, C A Gatsonis
Jan 11, 1990·The New England Journal of Medicine·H L NeedlemanE N Allred
Jul 1, 1989·Paediatric and Perinatal Epidemiology·D M FergussonJ M Lawton
Apr 1, 1989·Developmental Medicine and Child Neurology·M BergomiP L Tartoni
Nov 1, 1988·Journal of Child Psychology and Psychiatry, and Allied Disciplines·D M FergussonN G Kinzett
Nov 1, 1988·Journal of Child Psychology and Psychiatry, and Allied Disciplines·D M FergussonN G Kinzett
Jan 1, 1988·Journal of Child Psychology and Psychiatry, and Allied Disciplines·P A SilvaJ M Faed
Aug 25, 1988·The New England Journal of Medicine·A J McMichaelR J Roberts
Jan 1, 1985·Journal of the American Academy of Child Psychiatry·M Smith
Jan 1, 1986·International Archives of Occupational and Environmental Health·R LansdownJ Hunter
Dec 1, 1969·The American Journal of Psychiatry·C K Conners
Sep 1, 1983·Archives of Disease in Childhood

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Citations

May 8, 2000·Indian Journal of Pediatrics·B Kaul
Aug 7, 2012·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·L Eugene ArnoldElizabeth Hurt
Apr 29, 2004·Neurotoxicology and Teratology·Lisa M ChiodoJoseph L Jacobson
Jul 21, 2000·The Science of the Total Environment·S T Tong, K C Lam
Jul 1, 1998·The Science of the Total Environment·S T Tong, K C Lam
Nov 1, 2003·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·H L Needleman, D Bellinger
Apr 12, 2000·Neurotoxicology and Teratology·H GaravanB J Strupp
Oct 6, 2006·Social Biology·Lee Ellis
Nov 1, 2002·Journal of the American Academy of Child and Adolescent Psychiatry·Jeffrey D BurkeBoris Birmaher
Jan 9, 2008·Environmental Health : a Global Access Science Source·Nick Wilson, John Horrocks
Apr 3, 2001·Developmental Neuropsychology·T F CampbellM J Tobin
Oct 23, 2008·Environmental Health Perspectives·Hui-Li WangDi-Yun Ruan
Dec 23, 2006·Environmental Health Perspectives·Joe M BraunBruce P Lanphear
Dec 1, 1996·Environmental Health Perspectives·J P FawcettD B Menkes
Mar 31, 1998·American Journal of Public Health·G A WassermanJ Graziano
May 1, 1997·Journal of Child Psychology and Psychiatry, and Allied Disciplines·D M FergussonM T Lynskey
Oct 2, 2007·International Journal of Hygiene and Environmental Health·Wieslaw JedrychowskiIlona Lisowska-Miszczyk
Jan 18, 2003·Annals of Tropical Paediatrics·Abdur RahmanHina S Zuberi
Jan 2, 2007·Neurotoxicology and Teratology·Stéphane A BeaudinBarbara J Strupp
Jul 20, 1999·American Journal of Obstetrics and Gynecology·E EmoryF Sung
Feb 20, 2013·Clinical Psychology Review·James K GoodladJessica J Fulton
May 2, 1998·The Australian and New Zealand Journal of Psychiatry·F LevyG Sunohara
Jul 5, 2001·The Australian and New Zealand Journal of Psychiatry·D M Fergusson, L J Horwood
Dec 31, 1997·Journal of Child Psychology and Psychiatry, and Allied Disciplines·D M Fergusson, M T Lynskey
Feb 23, 2019·Nihon eiseigaku zasshi. Japanese journal of hygiene·Miyuki Iwai-ShimadaKyoko Nomura

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