Oct 30, 2018

Early detection of impending cryostorage tank failure using a weight-based monitoring system

BioRxiv : the Preprint Server for Biology
Zahava P MichaelsonZev Williams

Abstract

Objective: To study the ability of custom-built, web-enabled scales to monitor liquid nitrogen (LN2) levels in cryostorage dewars. Design: Laboratory study Setting: A large academic fertility center in New York City. Interventions: Cryostorage dewars were placed on top of the custom-engineered scales with continuous real-time monitoring, and weight and temperature data were recorded in the setting of slow, medium, and fast rate-loss of LN2 designed to mimic models of tank failures. Main Outcome Measures: Weights were continuously monitored and recorded, with a calculated alarm trigger set at 10% weight loss. Temperature within the tanks was simultaneously monitored with probes placed near the top of the tanks, with calculated alarms using a -185 degrees Celsius as the threshold. For the slow rate-loss simulations, tanks were left intact and closed in usual operating conditions, and LN2 was allowed to evaporate at the normal rate. For the medium rate-loss simulation, the foam core of the tank neck was removed and the insulating vacuum was eliminated by making a 1/16 inch hole in the outer tank wall. For the fast rate-loss simulation, a 1/16 inch hole was made through the outer tank wall and LN2 was released at a rate of 0.15 L/s...Continue Reading

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Mentioned in this Paper

Fertility
Study
Laboratory Studies
Alarm Reaction
Academic Medical Centers
Hydrophyllum capitatum
Liquid nitrogen
Bacillus sp. LN2.1
Infertility Study
Cryopreservation

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