Early detection of ulcerative colitis-associated colorectal cancer

Gastroenterology Report
Yu ZhenHu Zhang

Abstract

Colitis-associated colorectal cancer (CACC) is one of the most serious complications of inflammatory bowel disease (IBD), particularly in ulcerative colitis (UC); it accounts for approximately 15% of all-causes mortality among IBD patients. Because CACC shows a worse prognosis and higher mortality than sporadic colorectal cancer, early detection is critical. Colonoscopy is primarily recommended for surveillance and several advanced endoscopic imaging techniques are emerging. In addition, recent studies have reported on attempts to develop clinically relevant biomarkers for surveillance using various biosamples, which may become high-performance screening tools in the future, so the best approach and technique for cancer surveillance in long-standing UC patients remain under debate. This review gives a comprehensive description and summary about what progress has been made in terms of early CACC detection.

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Nov 22, 2018·Current Opinion in Clinical Nutrition and Metabolic Care·François BlachierEunjung Kim
May 17, 2019·Journal of Cellular Biochemistry·Sherien M El-DalyAmira M Gamal-Eldeen
Feb 11, 2020·Annual Review of Immunology·Shabnam Shalapour, Michael Karin
Apr 19, 2020·Medical Oncology·Jamal HallajzadehBahman Yousefi
Nov 19, 2019·Frontiers in Genetics·Zhen ZengHu Zhang
Sep 29, 2020·Expert Review of Gastroenterology & Hepatology·Eve BraithwaiteChristian P Selinger
Mar 8, 2020·Cells·Charles Robert LichtensternMichael Karin
Jun 3, 2021·International Journal of Molecular Sciences·Sana HibinoKoji Taniguchi

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