PMID: 61622Jan 1, 1976Paper

Early diagnosis of virus-caused vesicular rashes by immunofluorescence on skin biopsies. II. Poxvirus (vaccinia)

Scandinavian Journal of Infectious Diseases
E Olding-StenkvistA Espmark

Abstract

Immunofluorescence (IF) was used to demonstrate vaccinia virus antigen in frozen sections of skin biopsies from the site of revaccination in 42 individuals. The immunoglobulin (Ig) of a rabbit anti-vaccinia serum and the Ig of the pre-immune serum conjugated with fluorescein-isothiocyanate (FITC) was employed. 11/13 biopsies taken 1 day after vaccination were positive in the IF test as were 13/13 biopsies taken 2 days and 14/16 biopsies taken 3 days after vaccination. Even minute quantities of virus antigen were easily detected. The applicability of the test and the advantage of using biopsy material in early rashes of vaccinia and variola is discussed. The reliability of the direct IF using conjugated antisera against vaccinia-variola, varicella-zoster and herpes simplex virus for differentiating between maculopapular rashes was proved in a coded test.

References

Jan 1, 1976·Scandinavian Journal of Infectious Diseases·E Olding-StenkvistA Espmark
Jan 1, 1965·Acta Anaesthesiologica Scandinavica·D V Roberts, S Thesleff
Nov 1, 1967·Journal of Clinical Pathology·A L el-Ganzoury
Apr 20, 1963·Lancet·H G MURRAY

❮ Previous
Next ❯

Citations

Nov 1, 1993·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J L PérezR Martín
Jan 1, 1976·Scandinavian Journal of Infectious Diseases·E Olding-StenkvistA Espmark
Jan 1, 1988·Scandinavian Journal of Infectious Diseases·G SternerM Forsgren
Jan 1, 1980·Scandinavian Journal of Infectious Diseases. Supplementum
Sep 1, 1988·Journal of Clinical Microbiology·C A GleavesJ D Meyers
Sep 8, 2005·Journal of Clinical Microbiology·Daniel P FedorkoJeffrey I Cohen
Jul 1, 1982·Journal of Clinical Microbiology·N BalachandranW E Rawls
May 31, 2002·Journal of Clinical Microbiology·Mark J EspyThomas F Smith
Aug 1, 1984·Journal of the American Academy of Dermatology·T J Liesegang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.