Early epilepsy surgery

Current Neurology and Neuroscience Reports
S Wiebe

Abstract

Uncontrolled epilepsy is associated with progressive cortical and hippocampal atrophy, substantial cognitive and psychosocial morbidity, and increased mortality. Seizure freedom is required to reverse such morbidity and mortality. Surgery is vastly superior to medical therapy for patients with chronic, refractory temporal lobe seizures, and is now the standard of care for these patients. On the other hand, the concept of early surgery requires further exploration and definition. Although there is no robust, direct evidence to support early epilepsy surgery, case series and cohort studies report an association between earlier surgery and better outcomes. The evidence for earlier epilepsy surgery is reviewed.

References

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Citations

Jun 30, 2007·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·J G BurneoR S McLachlan
Sep 27, 2006·Dental Clinics of North America·Robert B Bryan, Steven M Sullivan
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Mar 5, 2008·Current Opinion in Neurology·John T Langfitt, Samuel Wiebe
Jan 26, 2008·The Neurologist·Vicente VillanuevaAntonio Gil-Nagel
Mar 15, 2006·Epilepsia·Christian HoppeChristian E Elger
Mar 25, 2020·Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko·A A ZuevO Yu Bronov
Sep 19, 2020·Journal of Neurosurgery. Pediatrics·Rafael Uribe-CardenasCaitlin E Hoffman

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