Early experience of a living donor kidney transplant program

European Urology
Antonio AlcarazHumberto Villavicencio

Abstract

Laparoscopic nephrectomy has been shown to reduce the morbidity of live donor nephrectomy, but post-transplant kidney function and safety issues with the procedure are still of some concern. The review of our early experience could detect errors that should be avoided in the refining of the technique. Our first sixty consecutive laparoscopic donor nephrectomies were analyzed retrospectively. There were conversions to open surgery (5%), all three in the first 18 cases. All donors were alive at 1 year with a glomerular filtration rate of 85+/-21 ml/min (78% of the basal). Patient and graft survival at 1 year was 100% and 95%, respectively. Creatinine nadir was achieved on post-transplant day 3 (creatinine, 176+/-122 micromol/l). Late renal function proved a continuous improvement until the 2-year follow-up (creatinine, 135+/-29 micromol/l). Renal function recovery was better in both recipient and donor when the donor was < or =50 years old, compared with older patients. Transplant complications that required reintervention included one ureteral fistula, one ureteral stenosis and one case of low renal flow that was re-vascularised. Technical surgical aspects such the use of Haemoloc clips in the clipping of the artery, the hand-as...Continue Reading

References

Oct 3, 1992·Lancet·J S NajarianA J Matas
Nov 4, 1998·Urology·J S WolfR M Merion
Sep 6, 2000·Annals of Surgery·E J SchweitzerS T Bartlett
Oct 12, 2000·The Journal of Urology·S C JacobsS T Bartlett
Jul 18, 2001·The Journal of Urology·M D StifelmanS Shichman
May 2, 2002·Archives of Surgery·Mathew C RawlinsThomas R Biehl
Oct 24, 2002·Transplantation·May Y LindJan N M IJzermans
Sep 27, 2003·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Christoph TroppmannRichard V Perez
Dec 11, 2003·The Journal of Urology·Stephen C JacobsStephen T Bartlett
Aug 19, 2004·Transplantation·Rebecca L TooherGuy J Maddern
Sep 24, 2004·Transplantation·John S GillBrian J G Pereira
Feb 22, 2005·BJU International·John M Barry
Mar 30, 2005·BJU International·Nasser SimforooshSeyed M M Hosseini Moghaddam
Apr 26, 2005·Transplantation Proceedings·R E SoulsbyM Shehata
May 13, 2005·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Jonathan T CarterAndrew M Posselt

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Citations

May 26, 2009·Actas urologicas españolas·Alfredo Aguilera BazánJavier de la Peña Barthel
Apr 14, 2011·Transplantation Proceedings·M AltinelA H Yazicioglu
Apr 27, 2010·European Urology·Francesco GrecoPaolo Fornara
Oct 16, 2007·European Urology·Tullio Sulser
Nov 5, 2014·Minimally Invasive Therapy & Allied Technologies : MITAT : Official Journal of the Society for Minimally Invasive Therapy·Marty ZdichavskyMarc Oliver Schurr
Oct 22, 2013·European Urology·Jim C HuHans A Gritsch

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