PMID: 9187997Jun 1, 1997Paper

Early extubation after mitral valve surgery: a target-controlled infusion of propofol and low-dose sufentanil

Journal of Cardiothoracic and Vascular Anesthesia
N D'AttellisJ F Baron

Abstract

In the current study, the use of a target-controlled infusion of low-dose propofol was combined with a continuous infusion of sufentanil for patients undergoing mitral valve surgery. The purpose of the study was to evaluate the hemodynamic stability, the time to awakening and spontaneous ventilation, and the feasibility in an early extubation setting of a total intravenous anesthetic technique. Prospective study. University hospital. Fifteen patients scheduled for elective mitral valve surgery. Induction of anesthesia consisted of sufentanil (1 microgram/kg), propofol (1 microgram/mL) target plasma concentration achieved over 3 minutes, and atracurium (0.5 mg/kg). The propofol target-controlled infusion was maintained at 1 microgram/mL throughout surgery and stopped at skin closure. A continuous infusion of sufentanil at 1.8 micrograms/kg/hr was started after induction and reduced to 0.9 microgram/kg/hr at the start of cardiopulmonary bypass and stopped at the end of bypass. Atracurium was infused at a rate of 0.5 mg/kg/hr up to sternal closure. No inhalation agents were used. Hemodynamic data were within normal limits. Six patients (40%) responded to verbal commands within 15 minutes postoperatively, 10 (67%) within the first ...Continue Reading

References

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Citations

Aug 24, 2002·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Dominique A BettexEdith R Schmid
Mar 28, 2001·The Annals of Thoracic Surgery·N D'AttellisJ N Fabiani
Mar 4, 2000·Journal of Cardiothoracic and Vascular Anesthesia·P CerianaA Bartoli
Mar 9, 1999·Journal of Cardiothoracic and Vascular Anesthesia·P OlivierJ F Baron
May 16, 1998·Journal of Cardiothoracic and Vascular Anesthesia·J M Manners

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