Early goal-directed therapy in moderate to high-risk cardiac surgery patients

Annals of Cardiac Anaesthesia
Poonam Malhotra KapoorUsha Kiran

Abstract

Early goal-directed therapy is a term used to describe the guidance of intravenous fluid and vasopressor/inotropic therapy by using cardiac output or similar parameters in the immediate post-cardiopulmonary bypass in cardiac surgery patients. Early recognition and therapy during this period may result in better outcome. In keeping with this aim in the cardiac surgery patients, we conducted the present study. The study included 30 patients of both sexes, with EuroSCORE >or=3 undergoing coronary artery bypass surgery under cardiopulmonary bypass. The patients were randomly divided into two groups, namely, control and early goal-directed therapy (EGDT) groups. All the subjects received standardized care; arterial pressure was monitored through radial artery, central venous pressure through a triple lumen in the right internal jugular vein, electrocardiogram, oxygen saturation, temperature, urine output per hour and frequent arterial blood gas analysis. In addition, cardiac index monitoring using FloTrac and continuous central venous oxygen saturation using PreSep was used in patients in the EGTD group. Our aim was to maintain the cardiac index at 2.5-4.2 l/min/m2 , stroke volume index 30-65 ml/beat/m2 , systemic vascular resistanc...Continue Reading

Associated Clinical Trials

Mar 3, 2020·Thepakorn Sathitkarnmanee

References

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Citations

Mar 1, 2013·British Journal of Anaesthesia·H D AyaA Rhodes
May 11, 2013·British Journal of Anaesthesia·M P W GrocottUNKNOWN Optimisation Systematic Review Steering Group
Jul 27, 2012·Interactive Cardiovascular and Thoracic Surgery·Mariateresa GiglioNicola Brienza
Aug 8, 2012·Critical Care : the Official Journal of the Critical Care Forum·John R ProwleRinaldo Bellomo
May 16, 2013·Critical Care : the Official Journal of the Critical Care Forum·Maurizio CecconiAndrew Rhodes
May 6, 2009·Critical Care : the Official Journal of the Critical Care Forum·Glenn HernandezAlejandro Bruhn
Oct 30, 2009·Critical Care : the Official Journal of the Critical Care Forum·Nicholas LeesAndrew Rhodes
Jul 17, 2014·Journal of Cardiothoracic and Vascular Anesthesia·Koichi SuehiroKiyonobu Nishikawa
Dec 7, 2014·Best Practice & Research. Clinical Anaesthesiology·Christiane Hartog, Frank Bloos
Feb 9, 2016·Journal of Cardiothoracic and Vascular Anesthesia·Stefano RomagnoliZaccaria Ricci
Aug 16, 2014·Critical Care : the Official Journal of the Critical Care Forum·Stefan ProbstJoerg Ender
Dec 18, 2013·Journal of Cardiothoracic and Vascular Anesthesia·Martin GeisenS Nicholas Fletcher
Nov 26, 2013·Journal of Cardiothoracic and Vascular Anesthesia·Byron D Fergerson, Gerard R Manecke
Feb 16, 2013·American Journal of Surgery·Mourad M AlsabbaghA Ahsan Ejaz
Jan 29, 2013·Best Practice & Research. Clinical Anaesthesiology·Matthew E Cove, Michael R Pinsky
Jul 31, 2012·Journal of Cardiothoracic and Vascular Anesthesia·Gerard R Manecke
Mar 27, 2012·Medicina intensiva·J L Pérez VelaUNKNOWN Grupo de Trabajo de Cuidados Intensivos Cardiológicos y RCP de SEMICYUC, con el aval científico de la SEMICYUC
Nov 22, 2011·Journal of Cardiothoracic and Vascular Anesthesia·Alexandre YazigiKhalil Jabbour
Oct 29, 2014·Critical Care : the Official Journal of the Critical Care Forum·Jan BenesFrederic Michard
May 25, 2011·The Journal of Thoracic and Cardiovascular Surgery·Marco RanucciUNKNOWN European Association of Cardiothoracic Anaesthesiologists
Oct 16, 2010·Journal of Cardiothoracic and Vascular Anesthesia·Marit HabicherMichael Sander
Sep 2, 2008·Best Practice & Research. Clinical Obstetrics & Gynaecology·Andrew Carlin, Zarko Alfirevic
Nov 7, 2015·BioMed Research International·Krisztián TánczosJózsef Kaszaki
Dec 3, 2014·Journal of Cardiothoracic and Vascular Anesthesia·Koichi SuehiroKiyonobu Nishikawa
Apr 22, 2015·Perioperative Medicine·Lais Helena Camacho NavarroGeorge C Kramer
Sep 12, 2014·Best Practice & Research. Clinical Anaesthesiology·Timothy E MillerTong J Gan
Aug 25, 2016·Journal of Cardiothoracic and Vascular Anesthesia·Pavel I LenkinMikhail Y Kirov
Sep 28, 2016·Journal of Cardiothoracic and Vascular Anesthesia·Vladimir V LomivorotovAlexander M Karaskov
Jul 7, 2018·Acta Anaesthesiologica Scandinavica·Thomas KaufmannIwan C C van der Horst

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