Early-life exposure to severe famine and subsequent risk of depressive symptoms in late adulthood: the China Health and Retirement Longitudinal Study

The British Journal of Psychiatry : the Journal of Mental Science
Changwei LiCheng Huang

Abstract

The Chinese Great Famine caused widespread starvation in 1959-1961. Its long-term association with depressive symptoms has not been studied.AimsTo estimate the burden of depressive symptoms and the association of famine exposure with depressive symptoms. The China Health and Retirement Longitudinal Study is a nationwide representative survey of 17 708 Chinese adults aged ≥45. Propensity score matching and modified Poisson regression were used to evaluate the association between self-reported famine exposure in early life and depressive symptoms among the overall participants. Such associations were also assessed by developmental stage using modified Poisson regression and logistic regression. The prevalence of depressive symptoms was 26.2% (95% CI 25.1-27.3%) in 2011. As defined by loss of family members because of starvation, 11.6% (95% CI 10.1-13.1%) of this population experienced severe famine. When compared with participants who did not experience starvation, those who had experienced severe famine during fetal, mid-childhood, young-teenage and early-adulthood stages had 1.87 (95% CI 1.36-2.55), 1.54 (95% CI 1.23-1.94), 1.47 (95% CI 1.09-2.00) and 1.77 (95% CI 1.42-2.21) times higher odds of having depressive symptoms in la...Continue Reading

References

Mar 23, 2004·American Journal of Epidemiology·Guangyong Zou
Jan 5, 2005·Archives of General Psychiatry·David M FergussonAnnette L Beautrais
Aug 4, 2005·JAMA : the Journal of the American Medical Association·David St ClairLin He
Oct 29, 2008·Proceedings of the National Academy of Sciences of the United States of America·Bastiaan T HeijmansL H Lumey
Aug 7, 2009·Human Molecular Genetics·Elmar W TobiBastiaan T Heijmans
Feb 18, 2010·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·Frank M BiroSteven R Daniels
Sep 28, 2010·Statistical Science : a Review Journal of the Institute of Mathematical Statistics·Elizabeth A Stuart
Dec 18, 2012·International Journal of Epidemiology·Yaohui ZhaoGonghuan Yang
Mar 20, 2013·Statistics in Medicine·Daniel F McCaffreyLane F Burgette
Sep 5, 2013·Archives of Gerontology and Geriatrics·Dan LiLin Tian
Aug 1, 2014·Nature·Hongshan GuoJie Qiao
Jun 1, 2011·Journal of Developmental Origins of Health and Disease·S R de RooijT J Roseboom
Nov 27, 2014·Nature Communications·Elmar W TobiBastiaan T Heijmans
Mar 13, 2016·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·M Gispert-LlauradoUNKNOWN NUHEAL Study Group

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Citations

Sep 22, 2020·JAMA Network Open·Yanjun MaWuxiang Xie
Sep 13, 2020·Clinical Psychology & Psychotherapy·Paola LongoEnrica Marzola
Dec 2, 2020·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Yingying SuXiangfei Meng
Jun 26, 2021·Stroke; a Journal of Cerebral Circulation·Chenglong LiWuxiang Xie

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