Early LSD treatment in Denmark from 1960 to 1974: An analysis of possible and long-lasting changes in the adult personality following psychedelic treatment. A historical retrospective cohort study.

Medicine
Jens Knud Larsen

Abstract

In view of the renewed interest in psychedelics in psychiatry it is timely to analyze psychedelic treatment in historical cohorts. Recently the therapeutic efficacy of psychedelics has been linked to the so-called phenomenon of "connectedness." The aim of the present study was to explore whether long-lasting personality changes were observed in any of the 151 Danish psychiatric patients who were treated with Lysergic acid diethylamide (LSD) from 1960 to 1974.The exploration included a reanalysis of a subgroup as well from a 1964 Danish historical cohort. Medical records and other case materials of the above mentioned 151 patients are kept in the Danish State Archives. The present author was granted access to the LSD case materials in the Danish State Archives, and respected confidentiality per the Archives Law. According to the LSD Damages Law from 1986, they all received financial compensation for LSD-inflicted harm.Analysis did not reveal any personality changes such as "connectedness;" however, other lasting personality changes were observed in 2 to 4 patients and in quite a few patients unwanted effects persisted for weeks or months following acute treatment. In the present analysis of the 1964 cohort, the same percentage o...Continue Reading

References

Feb 1, 1977·Acta Psychiatrica Scandinavica·E Brandrup, T Vanggaard
Jan 1, 1971·Archives of General Psychiatry·W H McGlothlin, D O Arnold
Jun 1, 1966·The American Journal of Psychiatry·M Rinkel
Nov 1, 1967·Archives of General Psychiatry·W McGlothlinM S McGlothlin
Oct 1, 1984·The Journal of Nervous and Mental Disease·R J Strassman
Oct 1, 1993·Addiction·H D Abraham, A M Aldridge
Apr 1, 1954·The Journal of Mental Science·R A SANDISONJ D WHITELAW
Jan 1, 1962·Nordisk psykiatrisk tidsskrift. Nordic journal of psychiatry·M HERTZ
Dec 2, 2008·CNS Neuroscience & Therapeutics·Torsten PassieAnnelie Hintzen
Feb 4, 2010·Journal of Psychiatric Research·James M BoltonJitender Sareen
Oct 1, 2011·Journal of Psychopharmacology·Katherine A MacLeanRoland R Griffiths
Mar 7, 2014·The Journal of Nervous and Mental Disease·Peter GasserRudolf Brenneisen
Aug 2, 2014·Therapeutic Advances in Psychopharmacology·David BaumeisterDerek Tracy
Mar 12, 2016·History of Psychiatry·Jens Knud Larsen
May 24, 2016·The Lancet. Psychiatry·Robin L Carhart-HarrisDavid J Nutt
Feb 16, 2017·History of Psychiatry·David ErritzoeRobin Carhart-Harris
Jul 21, 2017·Nordic Journal of Psychiatry·David Erritzoe, William A Richards
Aug 11, 2017·Psychopharmacology·R L Carhart-HarrisR Watts
Jun 13, 2019·Psychiatric Services : a Journal of the American Psychiatric Association·Hsueh-Han YehBrian K Ahmedani
Jan 14, 2020·History of Psychiatry·Petter Grahl Johnstad

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.