Early lung cancer detection and localization.

The Annals of Otology, Rhinology, and Laryngology
D R Sanderson, R S Fontana

Abstract

The Mayo Lung Project was established to develop and evaluate a screening program for early lung cancer in high-risk subjects. Men who are more than 45 years of age and who smoke one package of cigarettes or more daily are screened by the use of thoracic roentgenograms, three-day pooled sputum cytology, and lung health questionnaires at four-month intervals. These data are compared with data from similar subjects screened only on entry into the project. During the past three years, 34 patients who had no roentgenoraphic evidence of lung cancer were identified and examined because of carcinoma cells in sputum. Of these 34 patients, 27 have had bronchoscopic localization of their tumors and definitive treatment and 3 had upper respiratory tract neoplasms and also have been treated. Of the remaining four, one patient died suddenly after myocardial infarction and three patients have not had localization or treatment because of other severe complicating medical problems. Localization of roentgenographically occult lung cancer is reliable by the use of bronchofiberoscopy and meticulous, thorough sampling from the tracheobronchial tree. A search must be made for upper airway cancers in the same high-risk population, and the possibilit...Continue Reading

References

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Citations

Aug 12, 1998·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·M SatoS Fujimura
Mar 1, 1991·Current Problems in Cancer·D C Ihde, J D Minna
Jul 1, 1978·The Annals of Otology, Rhinology, and Laryngology·H B NeelD R Sanderson
Jul 1, 1981·The Annals of Otology, Rhinology, and Laryngology·H B NeelL B Woolner
Apr 17, 1999·Clinics in Chest Medicine·S Lam, H Shibuya

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