Early morbidity and neurodevelopmental outcome in low-birthweight infants born after third trimester bleeding

American Journal of Perinatology
A SpinilloS Guaschino

Abstract

Neonatal mortality, morbidity, and neurodevelopmental sequelae were compared between a consecutive series of 77 liveborn, low-birthweight (less than 2500 g) infants delivered after third trimester bleeding and 154 appropriate control infants of similar gestational age. Infants born after abruptio placentae had lower Apgar scores at 1 minute and higher rates of acidosis in comparison with control infants. In multivariate analysis, the infants in this group had higher risks of severe intraventricular hemorrhage and poor outcome (neonatal death or cerebral palsy) in comparison with control infants. In placenta previa, the infants had a higher prevalence of respiratory distress syndrome, whereas unclassified antepartum bleeding was associated with a high rate of neonatal hypoglycemia. After adjustment, by logistic regression analysis, for the effect of confounding factors (gestational age, birthweight, social class, and education of the mother), the risk of minor infant neurodevelopmental abnormalities at 2-year follow-up was increased in infants delivered after total or partial placenta previa or after unclassified antepartum bleeding. Third trimester bleeding should be considered a strong risk factor for both short-term neonatal ...Continue Reading

Citations

Apr 24, 1999·Obstetrics and Gynecology·J M CraneR Liston
Jan 29, 2003·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Yoshio MatsudaSatoshi Kouno
Jul 5, 2003·BJOG : an International Journal of Obstetrics and Gynaecology·Salma Imran KayaniCarrol Preston
Jul 8, 2014·Early Human Development·Ken FurutaHiroshi Sameshima
Dec 11, 2007·Archives of Gynecology and Obstetrics·Arie KoifmanEyal Sheiner
Oct 30, 2004·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·D K JamesC Chilvers
Sep 25, 2009·Paediatric and Perinatal Epidemiology·Marianne M HillemeierSteven A Maczuga
Apr 23, 2016·BJOG : an International Journal of Obstetrics and Gynaecology·C V AnanthM A Williams
Oct 16, 2007·Fetal Diagnosis and Therapy·Márta GávaiZoltán Papp
Aug 29, 2012·Obstetrical & Gynecological Survey·Kiran Prabhaker RaoJoseph A Spinnato
May 1, 2008·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·A HarlevE Sheiner

❮ Previous
Next ❯

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Absence Epilepsy

Absence epilepsy is a common seizure disorder in children which can produce chronic psychosocial sequelae. Discover the latest research on absence epilepsies here.

Related Papers

European Journal of Obstetrics, Gynecology, and Reproductive Biology
N M Rafla
Archives of Disease in Childhood. Fetal and Neonatal Edition
P J BeebyI D Rieger
© 2021 Meta ULC. All rights reserved