Early mortality after hip fracture surgery in COVID-19 patients: A systematic review and meta-analysis

Journal of Orthopaedics
Kevin C WangDavid A Forsh

Abstract

The aim of this systematic review and meta-analysis was to assess the risk of early mortality in hip fracture patients with COVID-19 infection who undergo surgical intervention. MEDLINE (PubMed) and CINAHL (Cumulative Index to Nursing and Allied Health Literature) databases. Studies were included in the systematic review if they reported postoperative mortality in patients with COVID-19 infection who underwent operative intervention for hip fracture. From this selection of studies, only investigations that reported postoperative mortality in a COVID-positive and a non-COVID group were included in the meta-analysis. Data regarding patient demographics, age, and sex were recorded. Additional data that was extracted included study location, data collection period, length of follow-up, COVID testing methodology, COVID testing results, and number of patients who underwent operative versus nonoperative management. The primary outcome of interest was postoperative mortality. Random effects meta-analyses were performed to assess the pooled relative risk of postoperative mortality according to COVID status. Odds ratios and 95% confidence intervals (CI) were calculated. The overall pooled mortality rate in the early postoperative period ...Continue Reading

References

Jul 12, 2002·Statistics in Medicine·Julian P T Higgins, Simon G Thompson
Dec 3, 2014·Injury·Vasanth SathiyakumarManish K Sethi
Aug 25, 2017·Geriatric Orthopaedic Surgery & Rehabilitation·Cornelis L P van de ReeTaco Gosens
Mar 8, 2019·Journal of Orthopaedic Trauma·Jesse D ChlebeckPatrick C Schottel
Mar 21, 2020·Lancet·Puja MehtaUNKNOWN HLH Across Speciality Collaboration, UK
Mar 24, 2020·The New England Journal of Medicine·Ezekiel J EmanuelJames P Phillips
Apr 8, 2020·Journal of the American Geriatrics Society·Zainab ShahidRohit Jain
Apr 10, 2020·The European Respiratory Journal·Rong-Hui DuHuan-Zhong Shi
Apr 16, 2020·Circulation·Peter P LiuHongliang Li
Apr 18, 2020·Journal of Thrombosis and Haemostasis : JTH·Marco RanucciLorenzo Menicanti
Apr 27, 2020·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Pietro Simone Randelli, Riccardo Compagnoni
Apr 30, 2020·The Journal of Bone and Joint Surgery. American Volume·Francesco CatellaniGennaro Fiorentino
May 8, 2020·The Journal of Bone and Joint Surgery. American Volume·Josep Maria Muñoz VivesUNKNOWN Spanish HIP-COVID Investigation Group
May 8, 2020·The Journal of Bone and Joint Surgery. American Volume·Bobin MiGuohui Liu
Jun 3, 2020·Journal of Orthopaedic Trauma·Kenneth A EgolUNKNOWN NYU COVID Hip Fracture Research Group
Jun 3, 2020·Journal of Orthopaedic Trauma·Drake G LeBrunWilliam M Ricci
Jun 19, 2020·Journal of Orthopaedics·Zoe B Cheung, David A Forsh
Jul 8, 2020·The Bone & Joint Journal·Babar KayaniFares S Haddad
Jul 18, 2020·Journal of the American Medical Directors Association·Clara BonanadAlberto Cordero
Jul 18, 2020·The Journal of Bone and Joint Surgery. American Volume·Janus Siu Him Wong, Kenneth Man Chee Cheung
Aug 11, 2020·Journal of Clinical Orthopaedics and Trauma·Anshul SobtiArshad Khaleel
Aug 21, 2020·Journal of Orthopaedic Trauma·Sanjit R KondaUNKNOWN NYU COVID Hip Fracture Research Group

❮ Previous
Next ❯

Citations

Jun 3, 2021·International Journal of Environmental Research and Public Health·Alberto GrassiStefano Zaffagnini
Jun 16, 2021·Journal of Orthopaedics and Traumatology : Official Journal of the Italian Society of Orthopaedics and Traumatology·Luigi ZagraClaudio Carlo Castelli
Jun 22, 2021·British Journal of Anaesthesia·T E F AbbottR M Pearse
Aug 4, 2021·The Journal of Clinical Endocrinology and Metabolism·Sara J Cromer, Elaine W Yu

❮ Previous
Next ❯

Methods Mentioned

BETA
PCR

Software Mentioned

STTGMA COVID
Review Manager ( RevMan )

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.